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Purinergic Receptors and their Modulators
This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design of purinergic receptor modulators and future challenges such as the availability of selective ligands for all receptor subtypes. Divided into 12 chapters, this comprehensive volume also offers a multidisciplinary perspective on the historical evolution, starting with a chapter devoted to the roots and early discoveries of adenosine and its receptors, followed by a twenty-year retrospective on the s...
A History of Private Life
Library has Vol. 1-5.
History of Universities
Volume XIX/1 of History of Universities contains the customary mix of learned articles, book reviews, conference reports and bibliographical information, which makes this publication such an indispensible tool for the historian of higher education. Its contributions range widely geographically, chronogically, and in subject-matter. The volume is, as always, a lively combination of original research and invaluable reference material.
Nuncius
Annali di storia della scienza.
New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications
This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses...
Time and the Ancestors
Time and the Ancestors: Aztec and Mixtec Ritual Art combines iconographical analysis with archaeological, historical and ethnographic studies and offers new interpretations of enigmatic masterpieces from ancient Mexico, focusing specifically on the symbols and values of the religious heritage of indigenous peoples.
Endocannabinoid Signaling
This second edition provides new and updated chapters detailing all major elements of the ECB system. Chapters guide readers through identification of drug targets, electrophysiology, computational chemistry, and machine learning. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Endocannabinoid Signaling: Methods and Protocols, Second Edition is a valuable resource for all researchers interested in learning more about this important and developing field.
The Roesler Franz Family and the Initiatic Path
Ettore Roesler Franz è stato una figura unica e di spicco tra i pittori romani ottocenteschi. Oltre a essere stato a conoscenza dei segreti degli iniziati, la fitta rete di amicizie e conoscenze che aveva con i maggiori esponenti culturali e artistici europei ha reso la sua pittura innovativa e densa di rimandi simbolici. Un artista completo e sensibile, dotato di una grande forza d'animo e una bontà che tanti ricordano. A collegarlo ad artisti come Leonardo da Vinci, Michelangelo, William Blake e Picasso è la massoneria, che come un filo attraversa cinquecento anni di storia dell'arte. E a raccontarci qui la sua intensa storia che si intreccia con quella dell'arte e di tanti uomini di cultura e arte è Francesco Roesler Franz, che con questo saggio ci lascia una testimonianza indimenticabile dell'artista mentre coglie l'occasione per riscoprire le origini della propria famiglia.
Die Magische Pforte
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