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The Dark Side of Reform
The Dark Side of Reform: Exploring the Impact of Public Policy on Racial Equity contains nine chapters on the development of social policies with the potential to advance racial equity. In addition to studying these policies and their implications, the chapters in this volume demonstrate how lessons from the past can be used to inform the direction of current discussions. At the heart of these conversations are concerns about whether Black people, in particular, will receive the full benefit of transformative laws that may emerge in the coming years. The volume also offers recommendations on implementing policies that address the unique concerns of structurally disadvantaged communities with particular emphasis on Black and Latinx people.
The Laws of Prosperity
A practical guide of life-changing wisdom and exercises to help restore health, abundance, spirituality, and genuine happiness from the author of the New York Times bestseller The Laws of Thinking. In his latest work, E. Bernard Jordan builds on his bestseller The Laws of Thinking to unveil more of the spiritual truths that dictate success and prosperity. Each of his twenty laws—from the law of employment to the law of values—is broken down into simple explanations and exercises to help the reader better understand their divine purpose. In this provocative book, Jordan demonstrates that when living in sync with God’s universal laws, economic hardship will disappear—you need only have faith, focus, and fundamental knowledge to succeed.
Synaptic Plasticity in Neurodegenerative Disorders
This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson's disease, Alzheimer's disease, and Huntington's disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational...
Therapeutic Oligonucleotides
This book provides a compelling overall update on current status of RNA interference
Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders
In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to improve the safety of gene therapy for genetic diseases. This comprehensive and authoritative overview of vector development is a necessary text for researchers, toxicologists, pharmacologists, molecular biologists, physicians, and students in these fields.
Oligonucleotide-Based Drugs and Therapeutics
A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic sc...
Young, Gifted, and Black
“An important and powerful book” that radically reframes the debates swirling around the academic achievement of African-American students (Boston Review) “The solutions offered by each essay are creative, inspirational, and good old common sense." —Los Angeles Times In 3 separate but allied essays, African-American scholars Theresa Perry, Claude Steele, and Asa Hilliard examine the alleged ‘achievement gap’ between Black and white students. Each author addresses how the unique social and cultural position Black students occupy—in a society which often devalues and stereotypes African-American identity—fundamentally shapes students’ experience of school and sets up unique o...
Uncommon Courage
'An extraordinary account of heroism and sacrifice. An unexpected and important story, rivetingly told. Rip roaring stuff. Get this into the paws of the sea dog in your life.' - Griff Rhys Jones 'A book that had to be written' - Let's Talk 'People ashore don't realise what a grim war we are waging at sea with the Germans. A cold-blooded war, in a way I think requiring the maximum of bravery from the men of both sides in the long run, as it is so ceaseless and intangible. You just don't know whether the next moment will be your last.' Robert Hichens, RNVSR Several years ago, Julia Jones was searching through long-forgotten items stored at her house and discovered some suitcases of old written...
