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Reviews recent experimental findings and current thinking on epithelial appendage morphogenesis. Contains sections on overview, morphogenesis of epithelial appendages on the body surface and within the body, molecular mechanisms, models, and approaches. Specific subjects include early molecular events in feather morphogenesis, evolutionarily conserved gene interactions, and molecular biology of anhidrotic ectodermal dysplasia. Many chapters contain summary diagrams of the formative process of organs, with cellular and molecular explanations. Annotation copyrighted by Book News, Inc., Portland, OR
This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Wound healing is critical for survival of multi-cellular organisms. This volume examines the underlying biological mechanisms and how they operate in different tissues within the body.
Feathers are one of the most unique characteristics of modern birds and represent the most complex and colourful type of skin derivate within vertebrates, while also fulfilling various biological roles, including flight, thermal insulation, display, and sensory function. For years it was generally assumed that the origin of flight was the main driving force for the evolution of feathers. However, various discoveries of dinosaur species with filamentous body coverings, made over the past 20 years, have fundamentally challenged this idea and produced new evolutionary scenarios for the origin of feathers. This book is devoted to the origin and evolution of feathers, and highlights the impact of palaeontology on this research field by reviewing a number of spectacular fossil discoveries that document the increasing morphological complexity along the evolutionary path to modern birds. Also featuring chapters on fossil feather colours, feather development and its genetic control, the book offers a timely and comprehensive overview of this popular research topic.
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. - Includes 20 color figures - Latest volume in series, with eight reviews in more than 250 pages - Topics covered include bone remodeling, ex vivo adult stem cell expansion, calcium sensing receptors and more
How high-level behaviors arise from low-level rules, and how understanding this relationship can suggest novel solutions to complex real-world problems such as disease prevention, stock-market prediction, and data mining on the Internet. The term "artificial life" describes research into synthetic systems that possess some of the essential properties of life. This interdisciplinary field includes biologists, computer scientists, physicists, chemists, geneticists, and others. Artificial life may be viewed as an attempt to understand high-level behavior from low-level rules -- for example, how the simple interactions between ants and their environment lead to complex trail-following behavior. An understanding of such relationships in particular systems can suggest novel solutions to complex real-world problems such as disease prevention, stock-market prediction, and data mining on the Internet. Since their inception in 1987, the Artificial Life meetings have grown from small workshops to truly international conferences, reflecting the field's increasing appeal to researchers in all areas of science.
Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field.This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds.