Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Competing-risk Outcomes After Hematopoietic Stem Cell Transplantation from the Perspective of Time-dependent Effects
Abstract: The success of hematopoietic stem cell transplantation is determined by multiple factors. Additional complexity is conferred by covariables showing time-dependent effects. We evaluated the effect of predictors on competing-risk outcomes after hematopoietic stem cell transplantation in a time-dependent manner. We analyzed 14951 outcomes of adult patients with hematologic malignancies who underwent a first allogeneic transplant. We extended the combined endpoints of disease-free and overall survival to competing-risk settings: disease-free survival was split into relapse and non-relapse mortality. Overall survival was divided into transplant-related mortality, death from other causes and death from unknown causes. For time-dependent effects we computed estimators before and after a covariable-specific cut-point. Patients treated with reduced intensity conditioning had a constantly higher risk of relapse compared to patients treated with myeloablative conditioning. For non-relapse mortality, patients treated with reduced intensity conditioning had a reduced mortality risk but this effect was only seen in the first 4 months after transplantation (hazard ratio: 0.76, P
Allogeneic Stem Cell Transplantation
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Blood Stem Cell Transplantation
Significant progress has been made in recent years in developing the use of peripheral blood as a source of stem cells for transplantation for patients with haematological and non-haematological malignancies. This book presents an overview of many of the scientific and technical advances that have been made, and discusses the clinical applications and results of transplants with blood-derived stem cells.
Enola Holmes 4: The Case of the Peculiar Pink Fan
Follow London's newest detective, Enola Holmes, in her fourth fantastic adventure - from the series that inspired the films, starring Millie Bobby Brown. Read them all before the next film lands! The ever-elusive Enola Holmes has now been on the run for more than eight months, much to the bemusement of her brother - the world's most famous detective, Sherlock Holmes. During a chance encounter with an old acquaintance, Lady Cecily, Enola realises that there is more to the young woman's plight than meets the eye. Especially when she leaves behind a dire plea for help within a peculiar pink fan . . . Puzzled, Enola finds she has no choice but to risk her freedom and join forces with Sherlock. But can she trust him? And can they both save Lady Cecily in time? Enola Holmes captivates in this sensational fourth adventure. 'A story of a young girl who is empowered, capable, and smart ... the Enola Holmes book series conveys an impactful message to kids and teenagers all over the world that you can do anything if you set your mind to it, and it does so in an exciting and adventurous way.' - MILLIE BOBBY BROWN
Haploidentical Transplantation
In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.
The Case of the Bizarre Bouquets: Enola Holmes 3
Everyone knows Dr. Watson is Sherlock Holmes' right-hand man - so when he goes missing, it's a shock. Even Sherlock hasn't the slightest clue as to where he could be. Enola is intrigued but wary; she's still hiding from her older brothers, and getting involved could prove to be disastrous. But Enola can't help but investigate, especially when she learns that a bizarre bouquet - with flowers all symbolizing death - has been delivered to the Watson residence. Enola knows she must act quickly, but can she find Dr. Watson in time?
The Woolly Bear Caterpillar
A beautifully illustrated marvellous minibeast tale from the bestselling Julia Donaldson and award-winning Yuval Zommer.Crawling through the garden, the little Woolly Bear Caterpillar wonders what kind of moth she will become. Bonny and bright, stunning and smart, but not kind, the other caterpillars laugh at the small, plain Woolly Bear. There is one thing that they are sure of: Woolly Bear could never be as dramatic and beautiful as them! But could one little caterpillar be about to undergo a truly terrific transformation?Brilliantly written and stunningly illustrated this engaging picture book comes complete with a nonfiction mini book about caterpillars and moths written by a nature specialist.
Think Big
What are you doing today to make your dream future come true? 'A rare self-help book that's actually informed by evidence. A host of perceptive, practical tips for getting out of your own way and making progress toward your career goals.' Adam Grant, bestselling author of Think Again and Originals 'A practical and accessible guide to using behavioural science in your career.' Caroline Criado Perez, author of Invisible Women ________________ We all have big ambitions for the future but those dreams only become reality if we do something towards them regularly. To achieve audacious goals, we need to take action and make small changes every day. We need to think big and act small. Drawing on cu...
