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Neural tube defects affect about 4000 pregnancies each year and are thus among the most common of severe birth defects. Prenatal diagnosis can now detect about 70% of neural tube defects but the tests produce many false positives, so the question is under what circumstances should they be recommended. This comprehensive volume - the collective knowledge of more than 55 experts in the field - provides lucid and authoritative discussions on this topic as well as on a wide variety of theoretical, experimental, and clinical issues.
Majoradvances in the diagnosis and treatment of oral clefts have been made in the past 50 years, and recent genetics and epidemiological studies have led to new theories about the causes of cleft lip and palate. Addressing issues that are relevant to clinicians, researchers and family members, this book is a comprehensive, well-illustrated, and up-to-date account of the many facets of this common disorder. The authors describe the embryological and molecular mechanisms of cleft causation, present and illustrate the genetic and epidemiological methods used to identify risk factors for oral clefts, and describe treatments by the various professionals of the cleft team. A section is also devoted to the integration of research findings into public health practice, including ethical and financial considerations. The book draws together such diverse disciplines as craniofacial development, gene mapping, epidemiology, medicine, ethics, health economics, and health policy and management, and it will be an invaluable reference work.
This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities. Recognizes that cilia and dynein arms play pivotal roles in developing mammalian embryos! Examines the rol
In Mary Shelley and the Rights of the Child, Eileen Hunt Botting contends that Frankenstein is a profound work of speculative fiction designed to engage a radical moral and political question: do children have rights?
Atherosclerosis is the most common cardiovascular disorder in western societies and is rapidly becoming similarly prevalent in the underdeveloped world. Written by notable authorities and providing text rich in illustrative figures, Molecular Mechanisms in Atherosclerosis addresses the fundamental mechanisms underlying atherothrombosis and delineat
Sickle cell first reported by James B Herrick; (Herrick 1910) a Chicago cardiologist and professor of medicine United States, in red blood cells. The disease was named "sickle-cell anaemia" by Verne Mason in 1922, then a medical resident at Johns Hopkins Hospital.(Konotey-Ahulu 2004) However, some elements of the disease had been recognized earlier: A paper in the Southern Journal of Medical Pharmacology in 1846 described the absence of a spleen in the autopsy of a runaway slave.
Congenital Heart Defects (CHDs) are the most frequently occurring birth defect, affecting over 25,000 infants a year in the US. This text serves as the definitive reference on the subject, coving all aspects of these malformations. The text includes chapters on the development, epidemiology, genetics, diagnosis, management and prevention of CHDs, and includes additional discussions of the public health and ethical issues of CHDs.
Obesity is a serious health issue and is a key discussion and research point in several disciplines from the social sciences to the health sciences and even in physical education. This text is a much-needed authoritative reference source covering major issues of, and relating to, obesity.
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