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Ladies and Gentlemen, dear colleagues, Welcome in Bodrum to the NASion Hot and Dense Nuclear Matter! Welcome also to Mrs. Governor Dr. Lale AYTAMAN. We are very honored, that you, Governor of the Mugla-State, came here to greet us. We are particularly grateful to you that you offered help and assured us to do everything that we can enjoy two safe weeks in Bodrum, in this wonderful area of your country. I have chosen Bodrum as the place for our NASI because I like this historic region where many cultures meet (e. g. , Oriental and European (Greek, Roman) culture) and where you find numerous places which played a role in ancient science and in early Christianity- I mention Milet (Thales) and E...
Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
Das vorliegende Buch richtet sich an Naturwissenschaftler mit ein- bis zweisemestriger Physik im Nebenfach sowie an Lehrer in Gymnasien und Fachschulen. Die Autoren sind als hervorragende Hochschullehrer bekannt und mit diesem Buch gelingt es ihnen, dem Leser das intuitive physikalische Denken zu vermitteln. Dies wird durch viele anschauliche Bilder unterstützt. Zu jeder wichtigen mathematischen Formel wird an Hand von Beispielen ihre Anwendung gezeigt und damit auch die Basis, selbst Probleme zu lösen, gegeben. Die Darstellung ist prägnant, trotzdem vermittelt sie dem Leser den heutigen Stand der Physik. Studenten, Lehrer und auch an den Naturwissenschaften Interessierte werden hier einen schnellen und effektiven Zugang zur modernen Physik finden.
Der Tipler bietet die gesamte Physik, wie sie in den ersten Semestern im Rahmen eines Bachelorstudiums in den Natur- und Ingenieurwissenschaften gelehrt wird. Die ausführlichen und leicht nachvollziehbaren Erklärungen sowie zahlreiche Rechenbeispiele, Tipps und Methoden machen dieses Buch zu einem beliebten Begleiter im Studium. Weitere Aufgabenstellungen zur Übung am Ende jedes Kapitels in verschiedensten Schwierigkeitsgraden sowie ein Crashkurs zum Nachschlagen der benötigten mathematischen Grundlagen helfen beim Ver- und Bestehen von Vorlesungen, Übungen und Klausuren. In der neuen Auflage werden Übungsbeispiele mit einer schrittweisen, anwendungsbezogenen Einführung in das Program...
th This workshop was the 15 in a series that addresses the subject of the dynamics of nuclear reactions. These workshops are dedicated to the concept that bringing together scientists from diverse areas of nuclear reactions promotes the vibrant exchange of ideas. This workshop hosted presentations from experimentalists and theorists, intermediate energy to ultrarelativistic energies, and final results to recent speculations. Many of these scientists would not normally be exposed to the work done in other subfields. Thus the Winter Workshop on Nuclear Dynamics plays a unique role in information exchange and the stimulation of new ides. The field of nuclear dynamics has a bright future. New ac...
Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain. - Neurogenic inflammation in historical perspective - Cardiac protection by nociceptive afferents - Molecular mechanisms of nociception - Sensory mechanisms in migraine pathophysiology - Vagal signaling of visceral inflammation - Neurogenic mechanisms in arthritis - Therapeutic implications of vanilloid-type compounds