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Ferroptosis in Stroke, Neurotrauma and Neurodegeneration, Volume II
This Research Topic is part of the Ferroptosis in Stroke, Neurotrauma and Neurodegeneration series: Ferroptosis in Stroke, Neurotrauma and Neurodegeneration Ferroptosis is a recently defined iron-dependent non-apoptotic form of cell death. Diverse stressors can destabilize metabolic processes in the cell, leading to excessive intracellular accumulation of reactive oxygen species that culminate in the collapse and rupture of the membrane structure of cellular organelles, such as mitochondria, endoplasmic reticulum, and lysosome. Ferroptosis is a form of cell death characterized by the accumulation of intracellular iron and lipid ROS. The primary morphologic manifestations of ferroptosis inclu...
Therapeutic Relevance and Mechanisms of Neuro-Immune Communication in Brain Injury
The brain is a critical organ with neuro-immune communication. The nervous system and immune system evolved to provide regulation of physiological homeostasis and protect against threats. Neuro-immune communication is correlated with physiological functions of various tissues and organs, and the internal environment balance. In brain trauma, the neural network is destroyed and the neuro-immune communication process is impaired. However, the research on this process is insufficient and limited. A thorough clarification of the cellular and molecular mechanisms of neuro-immune communication in brain injury is an essential necessary endeavor in the search for new therapeutic targets for brain injury. This Research Topic is devoted to the cellular and molecular mechanisms of neuro-immune communication in brain injury and on the meaningful exploration of how the nervous system regulates the immune system to promote neurofunctional recovery after brain injury.
Reviews in: Stroke
Frontiers in Neurology is delighted to present the ‘Reviews in’ series of article collections. Reviews in: Stroke will publish high-quality scholarly review papers on key topics in the field of Stroke. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries. We anticipate the research presented will promote discussion in the Stroke community that will translate to best practice applications in clinical, public health, and policy settings.
