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Current Advances in Precision Microscopy
The combination of multiplexing staining methods, new microscopic techniques, advanced computing power, and artificial intelligence opens new avenues in research and clinics for automated analysis of tissues, single cells as well as subcellular components, and even genetic parameters. A combination of biomarkers on protein, mRNA, and DNA levels supports the development of novel analytical/diagnostic approaches under the scope of precision medicine. In this Research Topic, we call for papers focusing on advanced light and in particular fluorescence microscopy and image/tissue cytometry applying methods of Machine and Deep Learning, as well as the combination thereof in automated analysis systems.
Gabriel's Insurrection
Perhaps no state rivals Virginia when it comes to early history. Yet, there are many aspects of Virginia's early history that are either unknown or vaguely known by the general public. Over the last thirty years, Larson has written over thirty plays that deal with these aspects and the generally well-known men and women involved in them. These people include such names as Thomas Jefferson, John Marshall, Patrick Henry, Meriwether Lewis, John Randolph, John Robinson, Nathaniel Bacon, William Berkeley, John Chiswell, Martha Jefferson, Harry Lee, Nancy Randolph, Theodosia Burr and Edmund Pendleton. The name Gabriel Prosser is little known, yet in the summer of 1800 this enslaved blacksmith planned to lead a large slave insurrection in the Richmond area; however information regarding the revolt was leaked prior to its execution and Gabriel's plans were thwarted. Gabriel and twenty-six members of the revolt were hanged. In 2007 Virginia Governor Tim Kaine gave Gabriel and his followers an informal pardon in recognition that his cause, "the end of slavery and the furtherance of equality for all people --- has prevailed in the light of history."
From Linguistics to Literature
Francis M. Rogers, to whom the current volume is in honor of, may be a modest man in principle, but not in his academic pursuits. To call his interests broad in scope is no exaggeration as they cover the fields of linguistics, literature, philology, bibliography, travel narratives and celestial navigation, which is nicely reflected in this volume. Part I concerns general and Luso-Brazilian linguistics (Bernard H. Bichakjian, John B. Jensen, Anthony J. Naro, Joseph M. Piel, Cléa Rameh); Part II Medieval studies: Sheila R. Ackerlind, Donald Stone Jr., Paolo Valesio, Joan B. Williamson; Part III Luso-Brazilian literature (Memória de Lázaro, Frederick C.H. Garcia, David T. Haberly, Jane M. Malinoff, Noami Hoki Moniz, Maria Luisa Nunes, Noêl W. Ortega, Raymond S. Sayers, Nelson H. Vieira); and Part IV on travel literature (Mary M. Rowan, Charity Cannon Willard). This volume also contains a complete bibliography of the writings of Francis M. Rogers.
Arcadia
Arcadia is a story of undying love and paranormal activity set during the tumultuous years of the American Civil War. Two children, Gabriel and Lorena found a very special, mystical place near their homes in the Appalachian hills of southern Ohio and claimed it as their own. They named it Arcadia and at this place, they grew up, fell in love and promised each other that they would be together for eternity. The Civil War separated the two for a while, a long while, but Lorena knew in her heart that someday Gabriel would return and they would once again be as happy as the first day they laid eyes on Arcadia. Some say that Arcadia was a place that God created and preserved for these two individ...
Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors
Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT...
Personalized Medicine in Anesthesia, Pain and Perioperative Medicine
This book discusses the current and future impact of cellular and molecular medicine (CMM) on anesthesiology and perioperative medicine. It covers the topic from a translational perspective and describes the relevance of CMM to daily clinical practice. Taking a bench-to-bedside approach, chapters examine topics including perioperative acute and chronic management, perioperative organ protection, and novel pharmaceuticals. Personalized Medicine in Anesthesia, Pain and Perioperative Medicine is aimed at anesthesiologists and pain physicians, and will also be of interest to pharmacists and those working in cellular and molecular medicine.
