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Brain Corticosteroid Receptors
Many psychiatric and neurological disorders have a genetic background, but it is unknown how the genes involved are regulated and expressed. It is recognised, however, that brain corticosteroid hormone receptors are extremely important in regulating the expression of genes involved in normal and pathological brain function.
Stress, the Brain and Depression
Can traumatic life events cause depression? Studies generally point to a connection between adverse life events and depression. However, establishing a causal rather than associative connection, the key concern of this book, is more problematic. What neurobiological changes may be induced by stress and depression, and to what extent do these changes correspond? The authors structure their examination around three major themes: the pathophysiological role of stress in depression; whether or not a subtype of depression exists that is particularly stress-inducible; and, finally, how best to diagnose and treat depression in relation to its biological underpinnings.
Tinnitus and Stress
This book provides up-to-date scientific information on the pathways by which psychosocial stress can affect the auditory system and describes current approaches to the management of patients with stress-related tinnitus. The latest evidence is presented on aspects such as the role of stress hormones in auditory function, the effects of allostatic load, circadian sensitivity to auditory trauma, and the association between stress-related biomarkers and tinnitus. The clinically oriented chapters discuss psychometric instruments of value in the tinnitus clinic and present stress-related tinnitus treatment protocols and outcome measures. It is widely acknowledged that the tinnitus percept acts a...
The Clinical Neurobiology of the Hippocampus
The hippocampus is one of the most studied structures in the human brain and plays a pivotal role in human memory function. Its recognized function is reflected by the presence of an extensive body of neurophysiological, neuropsychological, anatomical and neurocomputational literature that presents basic mechanisms, theoretical models and psychological concepts. However, in the rapidly growing field of hippocampal research, the clinical aspects of diseases that affect the hippocampus are greatly under-represented in current literature, and clinical approaches and concepts are scattered throughout various clinical and basic scientific disciplines. The Clinical Neurobiology of the Hippocampus ...
Pediatric Adrenal Diseases
Written by experts and specialized investigators, this book presents a detailed overview of the recent progress in our understanding of the adrenal cortex and its pivotal roles in homeostasis. Genes, molecules and cell compartments directly or indirectly involved in the complex steroidogenesis pathway as well as the resulting end-hormones glucocorticoids, mineralocorticoids and androgens are analyzed. Furthermore, the defects of the genes responsible both for common and rare adrenal disorders are presented. The interactions of the adrenal cortices with the adrenal medulla and their importance in the integration of adrenocortical and adrenomedullary function are discussed. The complex molecul...
Neuropeptides and Brain Function
NEUROPEPTIDES AND BRAIN FUNCTION.
Neuropeptides and Brain Function
Neuropeptides and Brain Function
