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Van der Waals Forces
This book should prove to be the definitive work explaining van der Waals forces, how to calculate them and take account of their impact under any circumstances and conditions. These weak intermolecular forces are of truly pervasive impact, and biologists, chemists, physicists and engineers will profit greatly from the thorough grounding in these fundamental forces that this book offers. Parsegian has organized his book at three successive levels of mathematical sophistication, to satisfy the needs and interests of readers at all levels of preparation. The Prelude and Level 1 are intended to give everyone an overview in words and pictures of the modern theory of van der Waals forces. Level 2 gives the formulae and a wide range of algorithms to let readers compute the van der Waals forces under virtually any physical or physiological conditions. Level 3 offers a rigorous basic formulation of the theory.
Management of Heart Failure
This volume presents a fresh international perspective on current approaches to treating heart failure. An accessible reference for hospital-based specialists, the book provides an update on recent advances in therapeutics and pharmacology, as well as ongoing trials. Four major sections concentrate on a review of screening, assessment and diagnosis; an update on drug treatments; an update on device therapy; and a description of best practice recommendations for managing clinically challenging cases
Food Hoarding in Animals
In this first comprehensive synthesis of the literature on food hoarding in animals, Stephen B. Vander Wall discusses how animals store food, how they use food and how this use affects individual fitness, why and how food hoarding evolved, how cached food is lost, mechanisms for protecting and recovering cached food, physiological and behavioral factors that influence hoarding, and the impact that hoarding animals have on plant populations and plant dispersal. He then provides detailed coverage of hoarding behavior across taxa—mammals, birds, and arthropods—to address issues in evolution, ecology, and behavior. Drawings, photographs, and appendixes document complex and intrinsically interesting food-hoarding behaviors, and the bibliography of nearly 1,500 sources is itself an invaluable and unique reference.
Myocardial viability
In the past few years it has become clear that left ventricular dysfunction, even of severe degree, may be reversible after coronary revascularization in some patients. As a result, myocardial viability has captured the imagination of researchers and clinicians seeking to unravel the cellular and subcellular mechanisms and define appropriate diagnostic modalities. These diagnostic modalities include: cardiac catheterization, positron-emission tomography, magnetic resonance imaging, two-dimensional echocardiography and single-photon imaging. This book, for the first time, brings together a diverse array of information in a comprehensive and concise fashion using a template of ten chapters written by experts in the field. It will be required reading for cardiologists, radiologists, nuclear medicine specialists, cardiac surgeons, anesthesiologists, internists and basic researchers and their trainees who are involved in the management of patients with coronary artery disease in whom myocardial viability is a clinically relevant issue.
Ultrafast MRI
The imaging potential of the MR experiment continues to evolve. In recent years, an increasing number of fast and ultrafast imaging strategies has been described. In this evolu tion the definition of the terms fast and ultrafast has been blurred. Hence they are frequently used interchangeably. The evolution of these methods has been based on two related, yet separate developments: an increasingly thorough understand ing of the complexities inherent to pulse sequence design and the increasing availability of stronger and faster gradient sys tems. The combination of these two factors has laid the foun dation for vast reductions of MRI data acquisition times. Min utes have been replaced by seco...
Spinoza, Life and Legacy
A biography of the boldest and most unsettling of the early modern philosophers, Spinoza, which examines the man's life, relationships, writings, and career, while also forcing us to rethink how we previously understood Spinoza's reception in his own time and in the years following his death. The boldest and most unsettling of the major early modern philosophers, Spinoza, had a much greater, if often concealed, impact on the international intellectual scene and on the early Enlightenment than philosophers, historians, and political theorists have conventionally tended to recognize. Europe-wide efforts to prevent the reading public and university students learning about Spinoza, the man and h...
Measurement of Cardiac Deformations from MRI: Physical and Mathematical Models
Measurement of Cardiac Deformations from MRI: Physical and Mathematical Models describes the latest imaging and imag analysis techniques that have been developed at leading centers for the visualization, analysis, and understanding of normal and abnormal cardiac motion with magnetic resonance imaging (MRI). The use of MRI in measuring cardiac motion is particularly important because MRI is non-invasive, and it is the only modality capable of imaging detailed intramural motion within the myocardium. Biomedical engineers, medical physicists, computer scientists, and physicians interested in learning about the latest advances in cardiovascular MRI should find this book to be a valuable educational resource. In particular, it is more tutorial in nature than most of the technical papers where the research was originally published. Practitioners and researchers working in the field of cardiovascular MRI will find the book to be filled with practical technical details and references to other work, enabling the implementation of existing methods and serving as a basis for further research in the area.
Metastasis
Metastasis is the most dreaded aspect of the carcinogenic process. More than ninety percent of all cancer deaths are attributable to the consequences of the primary tumor successfully colonizing distant organs. Unlike the situation with colon cancer, a patient with breast cancer can never be considered 'cured', since as many as a third of breast cancer patients who have apparently curative surgery for their primary tumors ultimately relapse with metastatic disease, sometimes decades later. Much effort is now devoted to understanding this process of metastasis, and finding ways to predict and prevent its occurrence.This publication covers recent advances in the field, specifically as they relate to breast cancer. The availability of new tools and technological approaches has prompted a reconsideration of the very definition of a metastasis. Furthermore, a number of commonly held myths are being explored and a new definition of a metastasis, with important implications for clinical staging, is being proposed. Also, a novel conceptual framework for cancer progression based on the system-level dynamics of regulatory networks is presented and the role of chemokines in mediating some of
Nuclear Cardiology and Cardiac Magnetic Resonance
Cardiovascular nuclear medicine emerged 15 years ago as a new noninvasive technique for the detection of human cardiac disease. It arised from the fields of nuclear medicine and cardiology and the cooperation of both specialties has been very productive. At present, nuclear cardiology techniques belong to the routine armamentarium of the clinical cardiologist. Results obtained by perfusion markers, metabolic tracers, and radionuclide angiography have shown to have important impact on patient management. Although exercise electrocardiography and echocar diography yield the large bulk of necessary data in the cardiac patient, nuclear cardiology provides important data that go far beyond the re...
From Basic Cardiac Imaging to Image Fusion
The recent development of three-dimensional imaging techniques has provided an enormous amount of information relevant to the clinical management of patients at low and high risk for coronary artery disease. However, while progress in each individual technique has been rapid, the correlation of findings obtained with radiology, nuclear medicine, and magnetic resonance imaging is still relatively neglected. In this book, qualified experts in cardiac imaging present the basic concepts of cardiac pathology and imaging and compare the findings obtained in particular subspecialties with those acquired using other techniques. In this way the reader will learn how images and techniques can be integrated in clinical practice to the benefit of the patient. In addition, it is explained how appropriate multimodality integration can reduce the patient's exposure to ionizing radiation. Physicians ranging from cardiac surgeons to internal medicine specialists and even public health administrators will find this book invaluable in understanding the role of hybrid cardiac imaging.
