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Medicinal Cannabis: Evolution of Therapeutic Use, Future Approaches and Other Implications, Volume II
This Research Topic is the second volume of its kind. Please see the publications of the first collection here. Cannabis has been used in even the oldest traditional medicines available. In the last century, somewhat negative attention has prevailed when it comes to the psychotropic and addictive effects and abuse potential; for this reason Cannabis has been banned and is illegal in many countries. In recent years, however, there has been a more in-depth evaluation of the legalization of cannabinoids for medical use in several countries following heightened media attention and reports of effectiveness, although not always thoroughly backed up by scientific evidence. In fact, up to now the re...
Biology of Brain Disorders
Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention. Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking a...
In vivo Models for Drug Discovery
This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects. After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, incl...
Jesuit Superior General Luis Martín García and His Memorias
Fr. Luis Martín García was superior general of the Society of Jesus during one of the most fractious periods in western history, from 1892 to his death in 1906. Fortunately for both the church and his order, he was endowed with remarkable gifts of mind and spirit. He was also troubled with personal challenges that he had to face almost entirely on his own. As an aid, he kept a memoir, prodigious in both size and content, to be published posthumously. The memoir appeared in a critical Spanish edition in 1988. In this present book, David Schultenover provides a condensed English version of it along with an interpretation that engages the question, why would a Jesuit superior general leave to posterity such a candid memoir? The subtitle “Showing Up” provides a clue.
