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Neurodegeneration Nanotechnology in Neurodegenerative Diseases
This book stems from the urgent necessity to address neurodegenerative diseases, which are among the most severe health challenges currently confronting society. Neurodegenerative diseases have become a major threat to public health in recent years, impacting millions of people globally and creating a substantial strain on healthcare systems and society as a whole. Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis are examples of these diseases. This book offers a thorough survey of the latest developments in this rapidly growing field. This book is targeted towards a wide range of readers, including academics, researchers, medical professionals, students, policy makers, and anybody else who is interested in the convergence of neuroscience, nanotechnology, and healthcare. Irrespective of one's familiarity with the subject, this book provides motivation and insightful information to bolster our group's endeavors in combating these debilitating diseases.
Verb and Context
This volume approaches the interaction of evidentiality with some other related categories, such as modality and mirativity, from an innovative angle: its connection to informational configuration. The aim of this book is to analyze the impact of shared knowledge on TAME categories as well as to explore its reflection on different verb choices. It provides an innovative theoretical view as well as a robust typological, crosslinguistic perspective.
Nanomedicine in Brain Diseases
This book provides an overview of the current applications of nanomaterials in brain diseases, and introduces several novel nanomaterials that have excellent potential in this field. During the last two decades, nanotechnology had matured significantly as it has transitioned from a bench-top science to an applied technology. However, the application of nanomaterials in basic and clinical neuroscience is still at an early stage, and understanding how the intrinsic properties of nanomaterials translate to complex biological responses is an area of intensive research. Part 1 of the book focuses on the principles and strategies of nanomedicine in the brain diseases, while part 2 examines the applications of promising nanomaterials for therapy and diagnosis in the brain. Together they offer a comprehensive picture of advances in nanotechnology and their successful use in treating brain diseases in the past 20 years.
Physiological Consequences of Brain Insulin Action
The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant to satiety and reward. Importantly, brains of Alzheimer ́s disease patients exhibit a signature of brain insulin resistance with perturbed brain metabolism. This book will cover the basics of insulin signaling in the brain and will describe concepts of insulin resistance, a feature of type 2 diabetes. Moreover insulin ́s effect on cognitive function will be pointed out and the association between...
The Masters of Medicine
An in-depth look at the mavericks, moments, and mistakes that sparked the greatest medical discoveries in modern times—plus the cures that will help us live longer and healthier lives in this century . . . and beyond. Human history hinges on the battle to confront our most dangerous enemies—the half-dozen diseases responsible for killing almost all of mankind. And while the story of our triumphs over these afflictions reveals an inspiring tapestry of human achievement, the journey was far from smooth. In The Masters of Medicine, Dr. Andrew Lam distills the long arc of medical progress down to the crucial moments that were responsible for the world’s greatest medical miracles. Discover ...
Natural Phenolic Compounds for Health, Food and Cosmetic Applications
Based on their potent antioxidant properties, the possible exploitation of natural phenolic compounds as food supplements as well as functional ingredients in the food and cosmetic industry is gaining more and more attention. This book contains original research articles and a review reporting innovative applications of natural phenolic compounds in the field of nutrition and biomedicine, as active ingredients for the prevention of oxidative-stress-related diseases, and as additives in smart food packaging, biomedical devices, and cosmetic products. The growing importance of agri-food wastes as easily accessible sources of phenolic compounds as well as of synthetic derivatives of natural compounds with improved antioxidant properties is also highlighted. Finally, novel technologies to improve extraction yields, stability, bioavailability, and delivery of antioxidant compounds for healthcare products or for skin applications are described.
Languacultural Hybridity and Translation
In an increasingly globalised world, the cultures of Orient and Occident are no longer firmly separated. This hybridity is also a part of literature—a concept which needs to be explored in Translation Studies. This study examines its evolution across language, culture, literature, and translation. It introduces a sociolinguistic approach for studying marginalized hybrid texts and their translations into English, focusing on the power dynamics that dichotomize the world into First/Third worlds. The author examines how sociological factors in central societies affect the acceptance and recognition of marginalized literary works within Western literary circles and world literature. The study analyses classical and modern Persian literature. It highlights the double-voicedness in these texts. By illustrating how hybrid elements from Rúmí’s mystical poems and Hidáyat’s surrealistic prose are recreated in their English translations, it elevates the analysis of hybrid elements to a languacultural level.
Nanoarchitectonics for Brain Drug Delivery
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
