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Pharmacotherapy of Diabetes: New Developments
Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types – 1 and 2 – of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine in general.
Story Of Interferon, The: The Ups And Downs In The Life Of A Scientist
The Finnish doctor Kari Cantell is one of the scientists to whom the development of the drugs called interferons can be attributed. Interferons have achieved an important place in the treatment of cancer, viral infections and multiple sclerosis. In the 1960s Cantell and his coworkers developed a method for the preparation of interferon in white blood cells. During those years, most of the global production of interferon took place in Finland and the vast majority of the clinical studies in the world employed Finnish interferon.The memoirs of Cantell record interferon's long road from the laboratory to the pharmacy shelf. The journey took more than three decades and involved moments of triump...
Diabetes: The Biography
Diabetes is a disease with a fascinating history and one that has been growing dramatically with urbanization. According to the World Health Authority, it now affects 4.6% of adults over 20, reaching 30% in the over 35s in some populations. It is one of the most serious and widespread diseases today. But the general perception of diabetes is quite different. At the beginning of the 20th century, diabetes sufferers mostly tended to be middle-aged and overweight, and could live tolerably well with the disease for a couple of decades, but when it occasionally struck younger people, it could be fatal within a few months. The development of insulin in the early 1920s dramatically changed things f...
The Kidney and Hypertension in Diabetes Mellitus
The first sporadic observations describing renal abnormalities in diabetes were published late in the 19th century, but systematic studies of the kidney in diabetes started only half a century ago after the paper by Cambier in 1934 and the much more famous study by Kimmelstiel and Wilson in 1936. These authors described two distinct features of renal involvement in diabetes: early hyperfiltration and late nephropathy. Diabetic nephropathy is, despite half a century of studies, still a very pertinent problem, renal disease in diabetes now being a very common cause of end-stage renal failure in Europe and North America and probably throughout the world. It is a very important part of the gener...
To Define and Inform
"To Inform and Define: An Analysis of Information Provided in Dictionaries Used by Learners of English in China and Denmark" presents a masterly synthesis of lexicographical theory in relation to bilingual and learner's dictionaries and advances a radical argument about how such dictionaries are used and how they should be improved for the convenience of students. By tracing the history of the terms 'semantic' and 'pragmatic' in linguistics and philosophy, Saihong Li shows the weakness of any conceptual distinction between them. She goes on to demonstrate how inappropriate these terms are for thinking about the ways in which words are defined and explained in dictionaries. The theoretical ar...
The Diabetic Kidney
A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
Continuity and Change in Grammar
One of the principal challenges of historical linguistics is to explain the "causes" of language change. Any such explanation, however, must also address the actuation problem: why is it that changes occurring in a given language at a certain time cannot be reliably predicted to recur in other languages, under apparently similar conditions? The sixteen contributions to the present volume each aim to elucidate various aspects of this problem, including: What processes can be identified as the drivers of change? How central are syntax-external (phonological, lexical or contact-based) factors in triggering syntactic change? And how can all of these factors be reconciled with the actuation problem? Exploring data from a wide range of languages from both a formal and a functional perspective, this book promises to be of interest to advanced students and researchers in historical linguistics, syntax and their intersection."
Textbook of Diabetes
Preceded by Textbook of diabetes / edited by Richard I.G. Holt ... [et al.]. 4th ed. 2010.
