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Charles Angrand
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Stem Cell Repair And Regeneration
Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.
Numerical Simulation of Compressible Euler Flows
The numerical simulation of the Euler equations of Fluid Dynamics has been these past few years a challenging problem both for research scientists and aerospace engineers. The increasing interest of more realistic models such as the Euler equations originates in Aerodynamics and also Aerothermics where aerospace applications such as military aircrafts and also space vehicles require accurate and efficient Euler solvers (which can be extended to more complicated modelisations including non-equilibrium chemistry) for su personic and hypersonic flows at high angles of attack and Mach number regimes involving strong shocks and vorticity. This book contains the proceedings of the GAMM Workshop on...
Cell Culture and Upstream Processing
Upstream processing refers to the production of proteins by cells genetically engineered to contain the human gene which will express the protein of interest. The demand for large quantities of specific proteins is increasing the pressure to boost cell culture productivity, and optimizing bioreactor output has become a primary concern for most pharmaceutical companies. Each chapter in Cell Culture and Upstream Processing is taken from presentations at the highly acclaimed IBC conferences as well as meetings of the European Society for Animal Cell Technology (ESACT) and Protein Expression in Animal Cells (PEACe) and describes how to improve yield and optimize the cell culture production process for biopharmaceuticals, by focusing on safety, quality, economics and operability and productivity issues. Cell Culture and Upstream Processing will appeal to a wide scientific audience, both professional practitioners of animal cell technology as well as students of biochemical engineering or biotechnology in graduate or high level undergraduate courses at university.
Numerical Methods for Nonlinear Variational Problems
This book describes the mathematical background and reviews the techniques for solving problems, including those that require large computations such as transonic flows for compressible fluids and the Navier-Stokes equations for incompressible viscous fluids. Finite element approximations and non-linear relaxation, and nonlinear least square methods are all covered in detail, as are many applications. This volume is a classic in a long-awaited softcover re-edition.
Lectures on Numerical Methods for Non-Linear Variational Problems
When Herb Keller suggested, more than two years ago, that we update our lectures held at the Tata Institute of Fundamental Research in 1977, and then have it published in the collection Springer Series in Computational Physics, we thought, at first, that it would be an easy task. Actually, we realized very quickly that it would be more complicated than what it seemed at first glance, for several reasons: 1. The first version of Numerical Methods for Nonlinear Variational Problems was, in fact, part of a set of monographs on numerical mat- matics published, in a short span of time, by the Tata Institute of Fun- mental Research in its well-known series Lectures on Mathematics and Physics; as m...
Embryonic Stem Cells
It is fair to say that embryonic stem (ES) cells have taken their place beside the human genome project as one of the most discussed biomedical issues of the day. It also seems certain that as this millennium unfolds we will see an increase in scientific and ethical debate about their potential utility in society. On the scientific front, it is clear that work on ES cells has already generated new possibilities and stimulated development of new strategies for increasing our und- standing of cell lineages and differentiation. It is not naïve to think that, within a decade or so, our overall understanding of stem cell biology will be as revolutionized as it was when the pioneering hemopoietic...
Cancer and Zebrafish
This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
Numerical Simulation of Compressible Navier-Stokes Flows
With the advent of super computers during the last ten years, the numerical simulation of viscous fluid flows modeled by the Navier-Stokes equations is becoming a most useful tool in Aircraft and Engine Design. In fact, compressible Navier-Stokes solvers tend to constitute the basic tools for many industrial applications occuring in the simulation of very complex turbulent and combustion phenomena. In Aerospace Engineering, as an exemple, their mathematical modelization requires reliable and robust methods for solving very stiff non linear partial differential equations. For the above reasons, it was clear that a workshop on this topic would be of interest for the CFD community in order to compare accuracy and efficiency of Navier-Stokes solvers on selected external and internal flow problems using different numerical approaches. The workshop was held on 4-6 December 1985 at Nice, France and organized by INRIA with the sponsorship of the GAMM Committee on Numerical Methods in Fluid Mechanics.
