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FCT
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Fc Receptors
This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after FcμR and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of FcεRI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, FcRs and Therapeutic Antibodies, the roles of various FcRs, including FcγRIIB and FcαRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.
The Chronicle
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Advanced Calculus
Suitable for a one- or two-semester course, Advanced Calculus: Theory and Practice expands on the material covered in elementary calculus and presents this material in a rigorous manner. The text improves students’ problem-solving and proof-writing skills, familiarizes them with the historical development of calculus concepts, and helps them understand the connections among different topics. The book takes a motivating approach that makes ideas less abstract to students. It explains how various topics in calculus may seem unrelated but in reality have common roots. Emphasizing historical perspectives, the text gives students a glimpse into the development of calculus and its ideas from the age of Newton and Leibniz to the twentieth century. Nearly 300 examples lead to important theorems as well as help students develop the necessary skills to closely examine the theorems. Proofs are also presented in an accessible way to students. By strengthening skills gained through elementary calculus, this textbook leads students toward mastering calculus techniques. It will help them succeed in their future mathematical or engineering studies.
THE RITUAL CONTAINING THE WORK, LECTURES AND MONITORIAL OF THE E. A., F. C. & M. M. DEGREES. ARRANGED AND COMPILED FROM THE STANDARD LODGE " WORK. " (1877)
This is a classic reprint of the original 1877, MASONIC BOOK AGENCY, first edition. " It contains the "work," lectures, and monitorial, of the ENTERED APPRENTICE, FELLOW CRAFT and MASTER MASONS' degrees, including everything pertaining to each."
Fc Mediated Activity of Antibodies
This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
Aplication in FCT
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