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The first study exploring the lives of female slaves of the Ottoman imperial court, drawing from hitherto unexplored primary sources
This book focuses on the similarities and differences between substance and non-substance addictions. It discusses in detail the mechanisms, diagnosis and treatment of substance and non-substance addictions, and addresses selected prospects that will shape future studies on addiction. Addiction is a global problem that costs millions of lives tremendous damage year after year. There are mainly two types of addition: substance addiction (e.g., nicotine, alcohol, cannabis, heroin, stimulants, etc.) and non-substance addiction (e.g., gambling, computer gaming, Internet, etc.). Based on existing evidence, both types of addiction produce negative impacts on individuals’ physical, mental, social and financial well-being, and share certain common mechanisms, which involve a dysfunction of the neural reward system and specific gene transcription factors. However, there are also key differences between these two types of addiction. Covering these aspects systematically, the book will provide researchers and graduate students alike a better understanding of drug and behavioral addictions.
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Digital violence continues to increase, especially during times of crisis. Racism, bullying, ageism, sexism, child pornography, cybercrime, and digital tracking raise critical social and digital security issues that have lasting effects. Digital violence can cause children to be dragged into crime, create social isolation for the elderly, generate inter-communal conflicts, and increase cyber warfare. A closer study of digital violence and its effects is necessary to develop lasting solutions. The Handbook of Research on Digital Violence and Discrimination Studies introduces the current best practices, laboratory methods, policies, and protocols surrounding international digital violence and discrimination. Covering a range of topics such as abuse and harassment, this major reference work is ideal for researchers, academicians, policymakers, practitioners, professionals, instructors, and students.
"A reissue of Ashton ESP research reports no. 1 (1981)." Originally published: Birmingham, England: Language Studies Unit, University of Aston in Birmingham, 1981.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, ...
The National Assessment of Educational Progress reveals that 37 percent of U.S. fourth graders fail to achieve basic levels of reading achievement. In 1997, the U.S. Congress asked that a review of research be conducted to determine what could be done to improve reading and writing achievement. The resulting "Report of the National Reading Panel: Teaching Children to Read" (NICHD, 2000) has been influential in helping to guide reading-education policy and practice in the United States. However, that report did not examine the implications of instructional practices used with children from birth through age 5. To address this gap in the knowledge base, the National Early Literacy Panel (NELP)...
This pocket-sized book is designed to provide up-to-date information for the general paediatrican and paediatric nephrologist, including advice on care of emergencies, chronic disorders and covering common and rare conditions. It is highly relevant for the day-to-day care of patients on the ward or in the outpatient clinic.
The grass or Poaceae family includes all cereal crops and forage grasses. Hence, they play a significant role in the economy of both the developed and developing world. Similar to other crop types, grasses are continuously challenged by a variety of environmental constraints. These constraints include a variety of biotic and abiotic stresses, and an enabling environment, which mainly refers to policy-related issues that affect productivity. In this book, the importance of selected cereal crops and grasses as well as associated constraints are presented. In addition, techniques proven to improve the productivity of these groups of crops are discussed. The techniques include variety development, soil and crop management practices, and biological control of fungal pathogens using different types of bacterial strains.
Reading Clocks, Alla Turca explores the technological and social aspects of Ottoman temporal culture, where religious and secular powers competed and colluded for authority, the army tried to rationalize its systems of training and communication, and schoolboys complained about how long classes were. The conflicts that played out on the field of temporal systems were not along the axes one might expect, with secular, urban, rationalist, modernizing, and Europeanizing forces arrayed against rural, traditional, religious, and nationalist people and parties. Rather, religious institutions saw the rationalization of temporal culture as a way to extend their authority (the muezzin s call to praye...