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Neuroanatomy and transgenic technologies
Neuroanatomists increasingly rely on techniques enabling them to manipulate genes in defined brain cell populations. In particular, engineered transgenes, which encode a variety of fluorescent reporter proteins can be inserted into the genome or delivered into desired brain regions using viral vectors, thereby allowing the labeling of molecularly-defined populations of neurons and/or glial cells. Transgenic technology can also be used to selectively delete genes in targeted neuronal populations or bi-directionally modulate their electrical excitability using optogenetic or chemogenetic techniques. One of the primary advantages of using transgenic reagents is to simplify the identification and tracing of targeted population of brain cells, which can be laborious using traditional techniques in neuroanatomy. In this research topic, we assembled up-to-date reviews and original articles that demonstrate the versatility and power of transgenic tools in advancing our knowledge of the nervous system, with a special emphasis on the application of transgenic technology to neuroanatomical questions.
Gene Regulatory Networks
Gene Regulatory Networks, Volume 139 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this release include Mouse hindbrain GRN, Xenopus endoderm GRN – organogenesis, Vertebrate limb GRN, The notochord gene regulatory network in chordate evolution: conservation and divergence from Ciona to vertebrates, Ciona early embryo GRNs, Boolean logic models, Modeling GRN response to morphogen gradient, GRN architecture, Theory of GRN evolution, Evolution of fly segmentation GRNs, GRN evolution in echinoderms, Evolution of network specificity, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on gene regulatory networks
A Demanda e a Defesa nas Execuções Cíveis e Fiscais
A natureza da obra é ímpar, essencialmente pela peculiaridade e perspicácia na reunião concomitante de dois ramos sensíveis do direito, no que concerne à matéria das execuções – o direito fiscal e o direito civil. A desmistificação e a simbiose fluída, no direito indicado, permite a todo o profissional forense, independentemente da sua afinidade com a matéria, de enriquecer os seus conhecimentos de forma extensiva. Paralelamente, habilitará o cidadão comum a reagir no momento justus, nas circunstâncias e termos adequados, e concede ao estudante a faculdade de juntar o executivo e o fiscal. Público-Alvo: Profissionais forenses Estudiosos e público em geral. Estrutura da ob...
Africa South of the Sahara 2004
A definitive one-volume guide to all sub-Saharan African countries, providing invaluable economic and directory data.
Europa World Year
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The Lusophone World
Portugal's European Union honeymoon has officially ended. It was the victim of a Europe-wide political and financial crisis and an unstable EU identity increasingly splintered along regional and economic fractures. What does this mean for the former good student of European democracy? The answer may lie in renewed Portuguese efforts to deepen and strengthen ties with Lusophone countries across the globe, which since 1996 have been organized into a supranational organization called the Community of Portuguese-Speaking Countries (CPLP). While Portugal's marginality in relation to Europe might be emphasized in the corridors of Brussels, within the realm of the CPLP the former world power can on...
Souto de Moura
"I look beyond solution; I look for an expression."--Eduardo Souto de Moura The architect Eduardo Souto de Moura (b. 1952) has won many accolades, including the 2011 Pritzker Architecture Prize. Based in Porto, Souto de Moura studied under Fernando Távora and worked under fellow Portuguese architect Álvaro Siza, with whom he continues to collaborate. Souto de Moura established his own practice in 1980, and his wide-ranging influences, including Mies van der Rohe and Donald Judd, can be seen in the stunning variety of his work, from his acclaimed private houses, to the striking Paula Rego Museum in Cascais and the Braga Municipal Stadium, to his work in historical contexts such as the Convento das Bernardas in Tavira. This beautifully illustrated retrospective provides the most comprehensive account of Souto de Moura's career to date. Drawings, notes and sketches from his archive, and newly commissioned photographs complement essays by scholars and prominent architects that trace Souto de Moura's career, contextualize his work within the larger trends of contemporary international architectural culture, and highlight the originality of his design strategy.
New Advances in Information Systems and Technologies
This book contains a selection of articles from The 2016 World Conference on Information Systems and Technologies (WorldCIST'16), held between the 22nd and 24th of March at Recife, Pernambuco, Brazil. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences and challenges of modern Information Systems and Technologies research, together with their technological development and applications. The main topics covered are: Information and Knowledge Management; Organizational Models and Information Systems; Software and Systems Modeling; Software Systems, Architectures, Applications and Tools; Multimedia Systems and Applications; Computer Networks, Mobility and Pervasive Systems; Intelligent and Decision Support Systems; Big Data Analytics and Applications; Human-Computer Interaction; Health Informatics; Information Technologies in Education; Information Technologies in Radiocommunications.
