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Neuroanatomy and transgenic technologies
Neuroanatomists increasingly rely on techniques enabling them to manipulate genes in defined brain cell populations. In particular, engineered transgenes, which encode a variety of fluorescent reporter proteins can be inserted into the genome or delivered into desired brain regions using viral vectors, thereby allowing the labeling of molecularly-defined populations of neurons and/or glial cells. Transgenic technology can also be used to selectively delete genes in targeted neuronal populations or bi-directionally modulate their electrical excitability using optogenetic or chemogenetic techniques. One of the primary advantages of using transgenic reagents is to simplify the identification and tracing of targeted population of brain cells, which can be laborious using traditional techniques in neuroanatomy. In this research topic, we assembled up-to-date reviews and original articles that demonstrate the versatility and power of transgenic tools in advancing our knowledge of the nervous system, with a special emphasis on the application of transgenic technology to neuroanatomical questions.
A Demanda e a Defesa nas Execuções Cíveis e Fiscais
A natureza da obra é ímpar, essencialmente pela peculiaridade e perspicácia na reunião concomitante de dois ramos sensíveis do direito, no que concerne à matéria das execuções – o direito fiscal e o direito civil. A desmistificação e a simbiose fluída, no direito indicado, permite a todo o profissional forense, independentemente da sua afinidade com a matéria, de enriquecer os seus conhecimentos de forma extensiva. Paralelamente, habilitará o cidadão comum a reagir no momento justus, nas circunstâncias e termos adequados, e concede ao estudante a faculdade de juntar o executivo e o fiscal. Público-Alvo: Profissionais forenses Estudiosos e público em geral. Estrutura da ob...
Gene Regulatory Networks
Gene Regulatory Networks, Volume 139 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this release include Mouse hindbrain GRN, Xenopus endoderm GRN – organogenesis, Vertebrate limb GRN, The notochord gene regulatory network in chordate evolution: conservation and divergence from Ciona to vertebrates, Ciona early embryo GRNs, Boolean logic models, Modeling GRN response to morphogen gradient, GRN architecture, Theory of GRN evolution, Evolution of fly segmentation GRNs, GRN evolution in echinoderms, Evolution of network specificity, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on gene regulatory networks
Radiotherapy of Liver Cancer
This book provides up-to-date information on all aspects of radiotherapy for liver cancer, from the basic science to clinical practice. While demand for radiotherapy of liver cancer has been increasing, the guidance available to clinicians has remained limited. Radiotherapy of Liver Cancer aims to address this deficit on the basis of the best available evidence. The first two sections explain the relevant basic science and present detailed information on the available technologies and techniques, including the most recent advances. The radiotherapy strategies appropriate in different patient groups are then fully described, covering the use of ablative, adjuvant, neoadjuvant, and definitive radiotherapy, radiotherapy as a bridge to liver transplantation, and palliative radiotherapy. The final section addresses a range of specific issues of concern to the clinician. Radiotherapy of Liver Cancer will be an ideal reference for clinical radiation oncologists, radiation oncology residents, oncologists, and hepatologists.
Immunotherapy Research and textbook 2
Research and textbook about new advances in immunotherapy.
Mobile Networks and Management
This book constitutes the thoroughly refereed post-conference proceedings of the Third International ICST Conference on Mobile Networks and Managements (MONAMI 2011) held in Aveiro, Portugal, in September 2011. The 30 revised full papers were carefully selected from numerous submissions and are organized thematically in 5 parts. These are mobile and wireless networks, self organized and mesh networks, new approaches for network visualization, network services, and security
Africa South of the Sahara 2004
A definitive one-volume guide to all sub-Saharan African countries, providing invaluable economic and directory data.
