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The Neurosciences and Music III
"This volume will be of particular interest to medical professionals, neuroscientists, neurologists, psychologists, educators, music therapists, musicologists, sound engineers, computer scientists. Manuscripts address how the tools of cognitive neuroscience have provided new insights into where and how rhythm is coded in the brain; production and perception abilities and the relationship between the two; the use of music as a tool for the investigation of human cognition and its underlying brain mechanisms; recent research investigating various aspects of musical memory and learning, and implications for medical rehabilitation for patients with memory disorders; advances in the fields of developmental auditory neuroscience, empirical music aesthetics, and music emotions in normal and disordered development such as autistic spectrum disorders; mutual interactions between music and language in children and adults with cochlear implants; and human communication of information, ideas, and emotional states, and the shared networks of speech and motor processing with musical processing"--NYAS Web site
Neurodevelopmental Disorders: Cognitive Behavioural Phenotypes
In recent years our approach to neurodevelopmental disorders has undergone extraordinary change. This has resulted from tremendous progress in various different disciplines including developmental neuroscience, behavioural and molecular genetics, and developmental neurobiology, and from the very high quality now achievable in neuroimaging and neurophysiological techniques. This publication aims to provide a concise and interdisciplinary approach to the study of the different cognitive/behavioural phenotypes encountered in a wide range of neurodevelopmental disorders. Starting from methodological, nosographic, and assessment premises, the book deals with selected disorders of a defined but still complex genetic aetiology, and concludes with a description of the neuropsychiatric disorders that are most commonly encountered during development.
Neurology of the Infant
Recent advances in the field of developmental neuroscience have been quite exciting, especially as they pertain to infants and children, in whom neurologic development proceeds more rapidly than at any other time of life So much has now been learned of normal neurologic development, which in tun informs the more pressing work of understanding how these normal functions become disordered by genetic, physical. or neurochemical mishaps. The information thus gained can, it is hoped, provide clinicians with the means to improve both their diagnostic and therapeutic tools and, more importantly, to use this understanding in the service of preventing or mitigating the effects of these childhood neurologic disorders. The physiologic and pathologic signs of neurologic diseases are better understood in the light of the current gains made in the fields of paediatric neurophysiology, neurochemistry, neuroimaging and genetics. This progress in knowledge can assuredly help the clinician to recognise the nature of the disorder and to plan the most appropriate and effective measures to improve the quality of the affected child's life.
Neurobiology, Diagnosis and Treatment in Autism
Autism is an extremely complex neurodevelopmental disorder that is expressed in a spectrum of phenotypes and is characterised by impaired reciprocal social communication and stereotyped patterns of interests and activities. Its aetiopathogenesis remains poorly understood. This exhaustive synthesis discusses various aspects: A focus on the neurobiology of autism: the candidate genes implicate an involvement of numerous brain regions and a concomitant malfunctioning of neurotransmitter, immunologic, and other mechanisms; The most incisive rehabilitation models in their original formulation and the results achieved with the same or similar protocols in Italian centres (understanding, language therapy, social skill training; The psychopharmacologic options for the condition of autism per se and for its associated, very frequent, comorbidities. It suggests a potential influence on professional practice and enables an up-to-date approach to effective diagnosis and treatment.
Mental retardation
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Hereditary Leukoencephalopathies and Demyelinating Neuropathies in Children
Genetically determined myelinopathies are a large group of neurological diseases that present a challenge to the clinician, the biologist and the geneticist. During the last decade, the development of tools for exploring the nervous system and the human genome has had a tremendous impact on the understanding of these diseases. Thus, the advances in neuroimaging techniques and molecular genetic research are continuously influencing disease classification, diagnostic protocols, and management of patients. These topics are the focus of the present publication. The aim is to provide a comprehensive review of the most important issues regarding genetic myelin disorders.
Perinatal brain damage
This volume is based on a highly successful conference dedicated to “Perinatal brain damage:from pathogenesis to neuroprotection ”. Neonatologists, paediatricians, paediatric neurologists, obstetricians, basic researchers involved in neurosciences, as well as rehabilitation professionals, will be interested by this ensuing publication. The volume covers pathogenic aspects of brain lesions occurring in the fetal and neonatal period, and addresses the issues of diagnostic workup and treatment.The most authoritative basic researchers, clinicians, and specialists in the field of neuroimaging, provide chapters on recent clinical advances. A subject of particular importance is the neurological...
Genetics of Epilepsy and Genetic Epilepsies
This volume provides updated information on epilepsy genes, on the clinical picture of genetic epilepsies discovered so far, and on conceptual advances in the complicated area of genotype-phenotype correlations. Recent studies on monogenic epilepsies present new insights into mechanisms whereby a mutation of a single gene, coding for an ion channel, can result in a complex epileptic phenotype. The analysis of genetically-determined epileptogenic dysplasia is advancing our understanding of the role of genes in controlling normal and pathological brain development. The pathogenic mechanisms by which gene mutations determine progressive myoclonus epilepsies offer critical opportunities to understand the role of genetic factors in neurodegenerative phenome-na associated with an even broader range of progressive epilepsy types. The specialists who have contributed to this book are outstanding international experts in their respective fields, ensuring first and foremost that the reviews are of relevance to clinicians dealing with epilepsy in their daily practice, as well as providing the highest quality scientific information for biomedical research.
Autistic Spectrum Disorders
Autism is a complex disorder of neurodevelopment resulting in pervasive abnormalities in social interaction and communication, repetitive behaviours and restricted interests. It presents difficult challenges to physicians and other professionals and especially to the parents and families of affected individuals. The aim of this volume is to provide an update on this multi-faceted condition, and to review most of its major features, in particular its biology, genetics and current understanding of its brain basis. The book emphasises the importance of early detection, and spells out appropriate steps for clinical diagnosis and investigations such as neuropsychology, electrophysiology and imaging. Of particular interest are chapters that focus on differential diagnosis, advances in neurogenetics and molecular biology, possible consequences of immunisations and the relation between autism and epilepsy.
