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The pharmaceutical industry is almost boundless in its ability to supply new drug therapies, but how does one decide which are the best medicines to use within restricted budgets? With particular emphasis on modeling, methodologies, data sources, and application to real-world dilemmas, Pharmacoeconomics: From Theory to Practice provides an introduc
In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.
Though sexual medicine is probably among the oldest of medical specialties, in fact not much was spoken about the subject till Kinsey published his first report in 1948. Speaking of sex was not considered a taboo by ancient civilizations, but this has not continued into the modern era. Herein lies the principle problem...patients and even doctors are not willing to openly discuss sexuality and sexual health. Healthcare professionals also fail to discuss these pertinent issues due to a lack of time, resources and general fear of causing offense. More importantly, there seems to be a lack of good training. Societies like the International Society of Sexual Medicine and European Society of Sexu...
Mafia Summit is the true story of how a small-town lawman in upstate New York busted a Cosa Nostra conference in 1957, exposing the Mafia to America In a small village in upstate New York, mob bosses from all over the country—Vito Genovese, Carlo Gambino, Joe Bonanno, Joe Profaci, Cuba boss Santo Trafficante, and future Gambino boss Paul Castellano—were nabbed by Sergeant Edgar D. Croswell as they gathered to sort out a bloody war of succession. For years, FBI director J. Edgar Hoover had adamantly denied the existence of the Mafia, but young Robert Kennedy immediately recognized the shattering importance of the Appalachian summit. As attorney general when his brother JFK became president, Bobby embarked on a campaign to break the spine of the mob, engaging in a furious turf battle with the powerful Hoover. Detailing mob killings, the early days of the heroin trade, and the crusade to loosen the hold of organized crime, fans of Gus Russo and Luc Sante will find themselves captured by this momentous story. Reavill scintillatingly recounts the beginning of the end for the Mafia in America and how it began with a good man in the right place at the right time.
This book is an analysis of twentieth-century historical fiction from Central America, tracing the active interplay between language, space, and memory.
From The Portuguese Original. Translated Into English With Notes Additions And Comments By A.X. Soares.
In this simple tale, the novel's hero is the talented heir to a notable family in Lisbon. He aspires to serve his fellow man in his chosen profession of medicine, in the arts, and in politics. But he enters a society affected by powerful international influences--French intellectual developments, English trading practices--that trouble and frustrate him. In the end he is reduced to a kind of spiritual helplessness and his good intentions are reduced to dilettantism. His passionate love affair begins to suffer a devastating constraint.
Una vez más la botadura de un barco lleno de ideas, de ideas expresadas a través de las palabras de los textos que conforman un libro. Un libro lleno de ideas transmitidas a través de los escritos claros de un conjunto de profesores y de arquitectos invitados a las clases de la Escuela TS de Arquitectura de Madrid. Todos ellos, los profesores que colaboran con el autor y los invitados, son extraordinariamente valiosos. Y todos ellos han elaborado unos textos certeros. Se ha querido respetar en el caso de los extranjeros la lengua original, para dar fe de universalidad. La estructura no sólo soporta, no sólo aguanta, sino que resuena, suena como un instrumento musical cuando es acordado ...
This text focuses on the complications following bariatric surgery. The focus is on the immediate and long term complications that would be important to both the general surgeon and those surgeons with specialty experience in bariatric surgery. Sections address the nutritional deficiencies following bariatric surgery with specific attention to Roux en Y gastric bypass and pancreatico-biliary diversion as well as the correction of these deficiencies with medical intervention as well as the indications for surgical revision or reversal. The text reviews the work-up of a bariatric patient with abdominal pain including the appropriate imaging and threshold for operative intervention and the tech...