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Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.
Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.
The number of cases of foot and ankle pathology and disorders has increased in the last two decades due to the way of life of the current human beings. On the one hand, there is the trauma category because of motorbike and car accidents; and on the other hand is the chronic syndromes due to everyday overuse of foot and ankle, as in high-demand sports and hobbies, as also in ballet dancing, etc. This book offers an updated guide to foot and ankle pathology and presents everyday trauma categories, as well as chondral and joint chronic syndromes at all ages from childhood to adulthood. Furthermore, the book will allow the reader to evaluate and realize how the foot changes during development from the early stages to adulthood. It also provides an overall outline of the anatomy and foot biomechanics, diagnosis of the pathologies, open or arthroscopic surgical approaches, treatment alternatives, and complications. Foot and Ankle Disorders - Pathology and Surgery will be of major interest for orthopedic residents, as well as for orthopedic surgeons at the first steps of their career, and for experienced ones seeking updated information.
The tibia is the larger, stronger, and anterior (frontal) of the two bones in the leg, which connects the knee with the ankle bones. The tibia, or shinbone, is the most fractured long bone in the body. In recent years, high-energy accidents result in comminuted tibia fractures or intraarticular fractures of the knee (plateau) or ankle (platform) that need immediate open reduction and internal fixation with anatomical plates or intramedullary nails. Intraarticular fractures with comminution or fractures with non-appropriate internal fixation predispose to post-traumatic knee or ankle arthritis. Conservative current therapies (injections of plate-rich plasma or stems cells) or high tibia osteotomies may delay the need of total knee arthroplasty. Tibia Pathology and Fractures analyzes all the up-to-date internal fixation or other operative or conservative therapies.
Selman Field was activated on June 15, 1942 and "trained over 15,000 navigators that flew in every theater of operation in WWII."--Page 7.
Prologue -- La Veinte: a Santa Monica barrio -- Rubén Ladrón de Guevara Sr., 1914-2006 -- 1742 22nd Street, Barrio La Veinte, Santa Monica -- Palm Springs / Cathedral City / Las Vegas -- Binnie -- La Gatita -- Las Vegas : breakup of the family -- Sue Dean -- Beverly -- Shindig! with Tina Turner and Bo Diddley, 1965 -- The Sunset Strip riots -- The southern belle -- LACC / The New Revelations Gospel Choir -- Miss Santa Barbara -- Frank Zappa / Ruben And The Jets / Rock 'n' Roll Angels / 1972-1974 -- Miss Pamela & the G.T.O.'s (Girls Together Outrageously) -- Miss Claremont -- Miss Chino -- The mutiny -- The movie star and Miss Blue Eyes -- We open for Zappa at Winterland, San Francisco, Apr...
By the dawn of the new millennium, robotics has undergone a major transformation in scope and dimensions. This expansion has been brought about by the maturity of the field and the advances in its related technologies. From a largely dominant industrial focus, robotics has been rapidly expanding into the challenges of the human world. The new generation of robots is expected to safely and dependably co-habitat with humans in homes, workplaces, and communities, providing support in services, entertainment, education, healthcare, manufacturing, and assistance. Beyond its impact on physical robots, the body of knowledge robotics has produced is revealing a much wider range of applications reach...
This book presents a compilation of topics related to primary total knee arthroplasty. The chapters cover, in a clear and didactic way, the current themes, written by experts from the area, from different parts of the world. Topics related to the three surgical phases (before surgery, during surgery, and after surgery) are discussed here. This is very important because the surgeon is not a "factory worker." First of all, it is a medicine doctor who has to feel and understand the particularities of each patient. Demographic studies show an aging population. Osteoarthritis and inflammatory diseases are becoming much more prevalent. In addition, a worldwide epidemic of trauma has led to the need for arthroplasties much more frequently. Therefore, total knee arthroplasty will be an increasingly important subject.
Knee Surgery - Reconstruction and Replacement is an intriguing book. From basic to advanced concepts, it collects relevant and reliable information obtained globally from validated collaborating researchers.
In recent years, the field of tissue engineering has begun, in part, to c- lesce around the important clinical goal of developing substitutes or repla- ments for defective tissues or organs. These efforts are focused on many tissues including skin, cartilage, liver, pancreas, bone, blood, muscle, the vascu- ture, and nerves. There is a staggering medical need for new and effective treatments for acquired as well as inherited defects of organs/tissues. Tissue engineering is at the interface of the life sciences, engineering, and clinical medicine and so draws upon advances in cell and molecular biology, mate- als sciences, and surgery, as well as chemical and mechanical engineering. Such an interdisciplinary field requires a broad knowledge base as well as the use of a wide assortment of methods and approaches. It is hoped that by bringing together these protocols, this book will help to form connections - tween the different disciplines and further stimulate the synergism underlying the foundation of the tissue engineering field.