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Drug Resistance in Leukemia &
The last ten years have seen the publication of a vast amount of data regarding cellular resistance to drugs in cancer cells. Recent studies have demonstrated that drug resistance assays appear to be predictive of clinical response and suggest that clinicians should now be considering the potential applications of these assays in the treatment of patients with hematological neoplasms. This collection of papers from the International Symposium on the Clinical Value of Drug Resistance Assays in Leukemia and Lymphoma, Amsterdam, 1992, provides a state-of-the-art discussion on drug resistance assays and their role in the design and individualization of treatment protocols.
AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
Deoxynucleoside Analogs in Cancer Therapy
Successful cancer chemotherapy relies heavily on the application of various deoxynucleoside analogs. Since the very beginning of modern cancer chemotherapy, a number of antimetabolites have been introduced into the clinic and subsequently applied widely for the treatment of many malignancies, both solid tumors and hematological disorders. In the latter diseases, cytarabine has been the mainstay of treatment of acute myeloid leukemia. Although many novel compounds were synthesized in the 1980s and 1990s, no real improvement was made. However, novel technology is now capable of elucidating the molecular basis of several inborn errors as well as some specific malignancies. This has enabled the ...
Deoxynucleoside Analogs in Cancer Therapy
Successful cancer chemotherapy relies heavily on the application of various deoxynucleoside analogs. Since the very beginning of modern cancer chemotherapy, a number of antimetabolites have been introduced into the clinic and subsequently applied widely for the treatment of many malignancies, both solid tumors and hematological disorders. In the latter diseases, cytarabine has been the mainstay of treatment of acute myeloid leukemia. Although many novel compounds were synthesized in the 1980s and 1990s, no real improvement was made. However, novel technology is now capable of elucidating the molecular basis of several inborn errors as well as some specific malignancies. This has enabled the ...
Standing at Water's Edge
Janice Post-White was an oncology nurse who thought she knew what life with cancer was about--until her four-year-old son was diagnosed with leukemia. While he drew pictures to process his emotions, she buried her feelings and threw herself into managing a dual role as a medical professional and mother. Her memoir shares her son's perspective as a young cancer patient and teen survivor, and explores her own personal and professional insights on survivorship, resilience, healing and what facing death can teach us about living.
Lectures on Finite Fields and Galois Rings
This is a textbook for graduate and upper level undergraduate students in mathematics, computer science, communication engineering and other fields. The explicit construction of finite fields and the computation in finite fields are emphasised. In particular, the construction of irreducible polynomials and the normal basis of finite fields are included. The essentials of Galois rings are also presented. This invaluable book has been written in a friendly style, so that lecturers can easily use it as a text and students can use it for self-study. A great number of exercises have been incorporated.
Cancer Cytogenetics
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Strindberg on Drama and Theatre
De Zweedse August Strindberg (1849-1912) wordt gezien als een van de meest belangrijke toneelschrijvers van rond de eeuwwisseling. Zijn choquerende theaterstukken had veel weerklank bij het publiek in die tijd, en inspireert tot op de dag van vandaag toneelschrijvers en publiek. Strindberg was een onophoudelijke innovator van verschillende theatervormen, een bron van inspiratie voor onder meer Eugene O'Neill, Samuel Beckett en Ingmar Bergman en heeft een vruchtbare bodem gelegd voor het moderne toneel. Zijn voorwoord voor Miss Julie en zijn inleiding bij A Dream Play zijn alom bekend en vaak herdrukt. Wat minder bekend is, is dat Strindberg veel toneelstukken recenseerde en kritieken schreef over het theater in z'n algemeen, en zijn toneelstukken in het bijzonder. Dit boek bevat de meest belangrijke van zijn kritieken, chronologisch weergegeven en geannoteerd, waarvan vele voor het eerst in het Engels.
Finite Fields And Galois Rings
A large portion of the book can be used as a textbook for graduate and upper level undergraduate students in mathematics, communication engineering, computer science and other fields. The remaining part can be used as references for specialists. Explicit construction and computation of finite fields are emphasized. In particular, the construction of irreducible polynomials and normal basis of finite field is included. A detailed treatment of optimal normal basis and Galoi's rings is included. It is the first time that the galois rings are in book form.
Single Cell Biomedicine
The book focuses on various detection targets applied in single cell studies, including tumor tissue cells, circulating tumor cells (CTCs), disseminated tumor cells (DTCs), circulating tumor DNA (ctDNA), cell-free DNA (cfDNA) and cancer stem cells (CSCs). It also discusses and compares detection methods using these detection targets in different fields to reveal single cell biomedical functions. The volume focuses not only on the methods already been established and validated, and also the methods newly developed. The book also highlights the importance and potential of single cell biomedicine in the development and validation of precision medicine strategies. It is useful for researchers and students in the field of cell biology, molecular medicine and precision medicine etc.
