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Membrane Physiopathology
The need for publishing acomprehensive review ofa number ofdifferent membrane pathologiesofmuscleand non-musclecells inillnesses ranging from diabetes toheart disease and cancer lies on to the fact that there are several books dealing with the properties ofnormal cell membranes, although there are very few books focussing on the abnormal membrane behavior. Since the membrane is the critical outer barrier of a cell, this membrane could be the first structure to be affected in some diseases. Research is advancing at the cellular level at a very rapid rate. We can now address questions such as: "How and by what is the mechanism underlying membrane ion channel and receptor dysfunction leading to...
Current Topics in Membranes and Transport
Current Topics in Membranes and Transport
Confocal Microscopy
This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology. These volumes provide a basic source for the quantitative interpretation of enzyme rate data and the analysis of enzyme catalysis. Among the major topics covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds, Transition State Determination, and Inhibitors.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Techniques in Confocal Microscopy
As part of the Reliable Lab Solutions series, Techniques in Confocal Microscopy brings together chapters from volumes 302, 307 and 356 of Methods in Enzymology. It documents many diverse uses for confocal microscopy in disciplines that broadly span biology. - Documents many diverse uses for confocal microscopy in disciplines that broadly span biology - The methods presented include shortcuts and conveniences not included in the initial publications - Techniques are described in a context that allows comparisons to other related methodologies - Methodologies are laid out in a manner that stresses their general applicability and reports their potential limitations
Liquid Life
If we lived in a liquid world, the concept of a "machine" would make no sense. Liquid life is metaphor and apparatus that discusses the consequences of thinking, working, and living through liquids. It is an irreducible, paradoxical, parallel, planetary-scale material condition, unevenly distributed spatially, but temporally continuous. It is what remains when logical explanations can no longer account for the experiences that we recognize as part of "being alive." Liquid life references a third-millennial understanding of matter that seeks to restore the agency of the liquid soul for an ecological era, which has been banished by reductionist, "brute" materialist discourses and mechanical mo...
Pathophysiology of Cardiovascular Disease
Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.
Taurine 2
This volume comprises the edited proceedings of the International Taurine Sympo sium held in Osaka, Japan, in June 1995, as a Satellite Symposium of the 15th Biennial of the International Society for Neurochemistry. This Taurine Symposium was the Meeting latest in a series held since 1975 at approximately two-year intervals by an informal group of international researchers. It attracted contributions from 20 countries, ranging from Armenia via Finland and Spain to the United States. Some 121 participants attended. The Symposium was organized and chaired by Junichi Azuma, University of Osaka. Other members of the Organizing Committee in Japan consisted of Kinya Kuriyama and Masao Nakagawa, bo...
In Vitro Methods in Toxicology
The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists.
Pulmonary Actions of the Endothelins
The biology of the family of endogenous autocrine peptides known as the endothelins (ETs) has been a source of intense study for researchers since 1988, following the identification of ET-l as the previously described endothelium-derived contractile factor. Initial interest focussed on the actions of the ETs in the cardiovascular system, and this remains the pri mary source of published work involving these peptides. Importantly, evi dence is mounting for a significant mediator role for ET-l in cardiovascu lar diseases including systemic hypertension and congestive heart failure. However, it was also recognized early on that the ETs exert an array of powerful actions in the respiratory tract...
Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research
This volume, the Proceedings of the 12th International Conference on Advances in Prostaglandin, Leukotriene and Other Bioactive Lipid Research: Basic Science and Clinical Applications, held August 25-29, 2002, in Istanbul, Turkey, discusses advances in bioactive lipid research with special attention to cancer, cardiovascular diseases, gastrointestinal diseases and respiratory diseases. Specific topics covered include the role of leukotrienes and lipoxins in inflammation, the cytochrome P450 pathway, the genetics and genomics of bioactive lipids, lipid peroxidation, apoptosis, angiogenesis, isoprostanes, receptors and inhibitors, cyclooxygenase and lipoxygenase pathways and inhibitors, prostaglandin synthases and receptor signaling, phospholipases and inhibitors.
