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Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Flow Chemistry in Drug Discovery
This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharma...
Interdisciplinary Bayesian Statistics
Through refereed papers, this volume focuses on the foundations of the Bayesian paradigm; their comparison to objectivistic or frequentist Statistics counterparts; and the appropriate application of Bayesian foundations. This research in Bayesian Statistics is applicable to data analysis in biostatistics, clinical trials, law, engineering, and the social sciences. EBEB, the Brazilian Meeting on Bayesian Statistics, is held every two years by the ISBrA, the International Society for Bayesian Analysis, one of the most active chapters of the ISBA. The 12th meeting took place March 10-14, 2014 in Atibaia. Interest in foundations of inductive Statistics has grown recently in accordance with the i...
Systematics and Evolution of Predatory Flower Flies (Diptera: Syrphidae) Based on Exon-capture Sequencing
Abstract: Flower flies (Diptera: Syrphidae) are one of the most species-rich dipteran families and provide important ecosystem services such as pollination, biological control of pests, recycling of organic matter and redistributions of essential nutrients. Flower fly adults generally feed on pollen and nectar, but their larval feeding habits are strikingly diverse. In the present study, high-throughput sequencing was used to capture and enrich phylogenetically and evolutionary informative exonic regions. With the help of the baitfisher software, we developed a new bait kit (SYRPHIDAE1.0) to target 1945 CDS regions belonging to 1312 orthologous genes. This new bait kit was successfully used ...
Practical Management of Pain
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their M...
Soft Methods for Integrated Uncertainty Modelling
The idea of soft computing emerged in the early 1990s from the fuzzy systems c- munity, and refers to an understanding that the uncertainty, imprecision and ig- rance present in a problem should be explicitly represented and possibly even - ploited rather than either eliminated or ignored in computations. For instance, Zadeh de?ned ‘Soft Computing’ as follows: Soft computing differs from conventional (hard) computing in that, unlike hard computing, it is tolerant of imprecision, uncertainty and partial truth. In effect, the role model for soft computing is the human mind. Recently soft computing has, to some extent, become synonymous with a hybrid approach combining AI techniques includi...
The Mathematics of the Uncertain
This book is a tribute to Professor Pedro Gil, who created the Department of Statistics, OR and TM at the University of Oviedo, and a former President of the Spanish Society of Statistics and OR (SEIO). In more than eighty original contributions, it illustrates the extent to which Mathematics can help manage uncertainty, a factor that is inherent to real life. Today it goes without saying that, in order to model experiments and systems and to analyze related outcomes and data, it is necessary to consider formal ideas and develop scientific approaches and techniques for dealing with uncertainty. Mathematics is crucial in this endeavor, as this book demonstrates. As Professor Pedro Gil highlig...
Introduction to Imprecise Probabilities
In recent years, the theory has become widely accepted and has been further developed, but a detailed introduction is needed in order to make the material available and accessible to a wide audience. This will be the first book providing such an introduction, covering core theory and recent developments which can be applied to many application areas. All authors of individual chapters are leading researchers on the specific topics, assuring high quality and up-to-date contents. An Introduction to Imprecise Probabilities provides a comprehensive introduction to imprecise probabilities, including theory and applications reflecting the current state if the art. Each chapter is written by expert...
