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Continuous Manufacturing for the Modernization of Pharmaceutical Production
  • Language: en
  • Pages: 69

Continuous Manufacturing for the Modernization of Pharmaceutical Production

On July 30-31, 2018, the National Academies of Sciences, Engineering, and Medicine held a workshop titled Continuous Manufacturing for the Modernization of Pharmaceutical Production. This workshop discussed the business and regulatory concerns associated with adopting continuous manufacturing techniques to produce biologics such as enzymes, monoclonal antibodies, and vaccines. The participants also discussed specific challenges for integration across the manufacturing system, including upstream and downstream processes, analytical techniques, and drug product development. The workshop addressed these challenges broadly across the biologics domain but focused particularly on drug categories of greatest FDA and industrial interest such as monoclonal antibodies and vaccines. This publication summarizes the presentations and discussions from the workshop.

Optimization of Pharmaceutical Processes
  • Language: en
  • Pages: 437

Optimization of Pharmaceutical Processes

Optimization of Pharmaceutical Processes presents contributions from leading authorities in the fields of optimization and pharmaceutical manufacturing. Formulated within structured frameworks, practical examples and applications are given as guidance to apply optimization techniques to most aspects of pharmaceutical processes from design, to lab and pilot scale, and finally to manufacturing. The increasing demand for better quality, higher yield, more efficient-optimized and green pharmaceutical processes, indicates that optimal conditions for production must be applied to achieve simplicity, lower costs and superior yield. The application of such methods in the pharmaceutical industry is not trivial. Quality of the final product is of major importance to human health and the need for deep knowledge of the process parameters and the optimization of the processes are imperative. The volume, which includes new methods as well as review contributions will benefit a wide readership including engineers in pharmaceuticals, chemical, biological, to name just a few.

Solving Large-Scale Production Scheduling and Planning in the Process Industries
  • Language: en
  • Pages: 299

Solving Large-Scale Production Scheduling and Planning in the Process Industries

  • Type: Book
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  • Published: 2018-10-01
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  • Publisher: Springer

This book presents a number of efficient techniques for solving large-scale production scheduling and planning problems in process industries. The main content is supplemented by a wealth of illustrations, while case studies on large-scale industrial applications, ranging from continuous to semicontinuous and batch processes, round out the coverage. The book examines a variety of complex, real-world problems, and demonstrates solutions that are applicable to scenarios and countries around the world. Specifically, these case studies include: • the production planning of the bottling stage of a major brewery at the Cervecería Cuauhtémoc Moctezuma (Heineken Int) in Mexico;• the production...

11th International Symposium on Process Systems Engineering - PSE2012
  • Language: en
  • Pages: 1804

11th International Symposium on Process Systems Engineering - PSE2012

  • Type: Book
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  • Published: 2012-09-09
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  • Publisher: Elsevier

While the PSE community continues its focus on understanding, synthesizing, modeling, designing, simulating, analyzing, diagnosing, operating, controlling, managing, and optimizing a host of chemical and related industries using the systems approach, the boundaries of PSE research have expanded considerably over the years. While early PSE research was largely concerned with individual units and plants, the current research spans wide ranges of scales in size (molecules to processing units to plants to global multinational enterprises to global supply chain networks; biological cells to ecological webs) and time (instantaneous molecular interactions to months of plant operation to years of st...

21st European Symposium on Computer Aided Process Engineering
  • Language: en
  • Pages: 2086

21st European Symposium on Computer Aided Process Engineering

  • Type: Book
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  • Published: 2011-06-10
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  • Publisher: Elsevier

The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, scientists, researchers, managers and students to present and discuss progress being made in the area of computer aided process engineering (CAPE). European industries large and small are bringing innovations into our lives, whether in the form of new technologies to address environmental problems, new products to make our homes more comfortable and energy efficient or new therapies to improve the health and well being of European citizens. Moreover, the European Industry needs to undertake research and technological initiatives in response to humanity's "Grand Challenges," described in the declaration of Lund, namely, Global Warming, Tightening Supplies of Energy, Water and Food, Ageing Societies, Public Health, Pandemics and Security. Thus, the Technical Theme of ESCAPE 21 will be "Process Systems Approaches for Addressing Grand Challenges in Energy, Environment, Health, Bioprocessing & Nanotechnologies."

Proceedings of the 2nd Annual Gas Processing Symposium
  • Language: en
  • Pages: 489

Proceedings of the 2nd Annual Gas Processing Symposium

  • Type: Book
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  • Published: 2010-06-29
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  • Publisher: Elsevier

Advances in Gas Processing: Proceedings of the 2nd Annual Gas Processing Symposium 11-1 4 January, 2010, Doha, Qatar, reviews the state of knowledge in gas processing. The contributions are organized around five main themes: (i) environmental sustainability; (ii) natural gas processing technologies; (iii) energy efficiency in operations; (iv) design and safety; and (v) operational excellence. The papers on environmental sustainability cover topics such as the biogasification of waste monoethanolamine; the role of LNG in a carbon constrained world; and sustainable water management. The papers on natural gas processing technologies include the removal of acid gases from natural gas streams via...

10th International Symposium on Process Systems Engineering - PSE2009
  • Language: en
  • Pages: 1229

10th International Symposium on Process Systems Engineering - PSE2009

  • Type: Book
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  • Published: 2009-09-14
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  • Publisher: Elsevier

The 10th International Symposium on Process Systems Engineering, PSE'09, will be held in Salvador-Bahia, Brazil, on August 16–20, 2009. The special focus of PSE 2009 is Sustainability, Energy, and Engineering.PSE 2009 is the tenth in the triennial series of international symposia on process systems engineering initiated in 1982. The meeting brings together the worldwide PSE community of researchers and practitioners who are involved in the creation and application of computing-based methodologies for planning, design, operation, control and maintenance of chemical and petrochemical process industries. PSE'09 will look at how PSE methods and tools can support sustainable resource systems, emerging technologies in the areas of green engineering, and environmentally conscious design of industrial processes.- sustainable resource systems - emerging technologies in the areas of green engineering - environmentally conscious design of industrial processes

19th European Symposium on Computer Aided Process Engineering
  • Language: en
  • Pages: 1341

19th European Symposium on Computer Aided Process Engineering

  • Type: Book
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  • Published: 2009-06-12
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  • Publisher: Elsevier

The 19th European Symposium on Computer Aided Process Engineering contains papers presented at the 19th European Symposium of Computer Aided Process Engineering (ESCAPE 19) held in Cracow, Poland, June 14-17, 2009.The ESCAPE series serves as a forum for scientists and engineers from academia and industry to discuss progress achieved in the area of CAPE.* CD-ROM that accompanies the book contains all research papers and contributions * International in scope with guest speeches and keynote talks from leaders in science and industry * Presents papers covering the latest research, key top areas and developments in computer aided process engineering (CAPE)

10th International Symposium on Process Systems Engineering
  • Language: en
  • Pages: 1229

10th International Symposium on Process Systems Engineering

  • Type: Book
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  • Published: 2009
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  • Publisher: Elsevier

The 10th International Symposium on Process Systems Engineering, PSE'09, will be held in Salvador-Bahia, Brazil on August 16-20, 2009. The special focus of PSE 2009 is Sustainability, Energy and Engineering. PSE 2009 is the tenth in the triennial series of international symposia on process systems engineering initiated in 1982. The meeting is brings together the worldwide PSE community of researchers and practitioners who are involved in the creation and application of computing-based methodologies for planning, design, operation, control and maintenance of chemical and petrochemical process industries. PSE'09 will look at how the PSE methods and tools can support sustainable resource systems and emerging technologies in the areas of green engineering: environmentally conscious design of industrial processes. PSE methods and tools support: - sustainable resource systems - emerging technologies in the areas of green engineering - environmentally conscious design of industrial processes

Directory of Graduate Research
  • Language: en
  • Pages: 1928

Directory of Graduate Research

  • Type: Book
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  • Published: 2005
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  • Publisher: Unknown

Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.