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This book is a collection of chapters on happiness and well-being. It includes contributions from scientists from all over the world, who present different, multifaceted, dialectically open perspectives and sensitivities regarding happiness. The authors discuss happiness and well-being from biological, biopsychosocial, anthropological, and philosophical points of view.
Literary tourism is a nascent field in tourism studies, yet tourists often travel in the footsteps of well-known authors and stories. Providing a wide-ranging cornucopia of literary tourism topics, this book fully explores the interconnections between the written word and travel. It includes tourism stories using guidebooks, films, television and electronic media, and recognises that stories, texts and narratives, even if they cannot be classified as traditional travel writing, can become journeys in themselves and take us on imaginary voyages. Appealing to a wide audience of different disciplines, it encompasses subjects such as business literary writing, historical journeys and the poetry of Dylan Thomas. The use of these different perspectives demonstrates how heavily and widely literature influences travel, tourists and tourism, making it an important read for researchers and students of tourism, social science and literature.
Since the first attempts at structure-based drug design about four decades ago, molecular modelling techniques for drug design have developed enormously, along with the increasing computational power and structural and biological information of active compounds and potential target molecules. Nowadays, molecular modeling can be considered to be an integral component of the modern drug discovery and development toolbox. Nevertheless, there are still many methodological challenges to be overcome in the application of molecular modeling approaches to drug discovery. The eight original research and five review articles collected in this book provide a snapshot of the state-of-the-art of molecula...
This insightful volume critically explores activist events in their scale and their capacity to attract media attention through a critical event studies lens, offering new perspectives on protests and social movement. This book conceives events of dissent as the public manifestation of counter-narratives that articulate advocacy for policy change. It focuses on the material and virtual manifestation of protest events and the media response to them, associated with three active social movements – Reclaim These Streets, Extinction Rebellion, and Black Lives Matter. In doing so, the text sheds light on how different political orientations within the media articulate the representation of even...
This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to...
This timely and innovative book offers an introduction to a range of creative methods, providing both empirical and conceptual guidance. Based upon existing empirical work and richly illustrated throughout, each chapter carefully examines creative methodology and/or methods within an event and festival context. International case studies are incorporated throughout, providing real-world examples of how these methods have been used in practice, as well as highlighting potential ethical issues. Each chapter includes a concise ‘how to’ set of guidelines to help researchers and students employ creative methods in their own work, as well as a series of ‘think points’ to help develop ethical practices. Chapters illustrate new pathways or lessons learned from research during the pandemic and other challenging landscapes. This significant volume offers festival and event researchers and students a different approach to their work that could result in better research, reaching hidden and marginalised groups.
Innovative and the first of its kind, this informative and multidisciplinary book explores the socio-cultural significance inherent in event infrastructures. While mainstream event management literature addresses event infrastructures mainly through its operational relevance, this carefully compiled edited volume takes infrastructures as an analytical point in respect to its social, political, economic and cultural potential of the study of events. Borrowing from the ongoing social scientific debates on the geography, sociology and anthropology of infrastructures, critical questions are posed in relation to the event contexts. With references to events in Argentina, Malawi, Spain and the UK, among others, the volume combines an international perspective with a highly relevant subject for contemporary event management education. By bringing together theoretical as well as empirical readings on the question of event infrastructures from a critical point of view, the debates are relevant to practitioners and researchers as well as undergraduate and postgraduate students in the field of events, leisure, tourism, anthropology, sociology, geography and urban planning – among others.
This book offers a fresh perspective on how computational tools can aid the chemical biology research community and drive new research.
Huntington's Disease is one of the well-studied neurodegenerative conditions, a quite devastating and currently incurable one. It is a brain disorder that causes certain types of neurons to become damaged, causing various parts of the brain to deteriorate and lose their function. This results in uncontrolled movements, loss of intellectual capabilities and behavioural disturbances. Since the identification of the causative mutation, there have been many significant developments in understanding the cellular and molecular perturbations. This book, "Huntington's Disease - Core Concepts and Current Advances", was prepared to serve as a source of up-to-date information on a wide range of issues ...