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NeuroPhytomedicine
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: • Applications of phyto-nanotechnology in neurological ailments, • Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders, • Epigenetic relevance pertaining to modulation by phytochemicals. The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.
Focus on Chronic Pain: Neuropathological Mechanism, Clinical Diagnosis and Treatment
Pain is an unpleasant sensory and emotional experience and the most frequent causes for patients to seek medical care. Persistent chronic pain affects millions of people worldwide, causing low quality of health and emotional status, as well as posing a significant social and economic burden. Chronic pain is the long-standing pain that are classified as different types, including chronic primary pain and secondary pain types caused by various diseases. The complexity of cause and symptom in chronic pain is associated with changes in different levels of nervous system, from molecular interaction, synaptic connection, cellular response, and neural circuits. The development of new treatments to manage chronic pain shall base on the better standing of the neuropathological mechanism underlying the symptom, the exploration on the methods of a better diagnosis, and the communication of clinical application standards and results.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Los Fueros del Reino de Toledo y Castilla La Nueva
Desde la reconquista de Toledo, el 25 de mayo de 1085, hasta la batalla de las Navas de Tolosa, en 1212, que abrió al mundo cristiano la reconquista de las tierras de Andalucía, tres monarcas castellanos vertebraron jurídicamente el actual espacio castellano-manchego. Así, Alfonso VI, rey conquistador de Toledo, hasta el triunfador de las Navas de Tolosa, Alfonso VIII, rey de Castilla y Toledo, pasando por el «Emperador de toda la España», Alfonso VII, fueron los encargados de la concesión de fueros, primero a la ciudad de Toledo, después a las ciudades y villas incorporadas al, ahora, reino cristiano de Toledo y, finalmente, el resto de villas y ciudades que conformaron la nueva Ca...
Vibrio ecology, pathogenesis and evolution
Vibrios are Gram-negative bacilli that occur naturally in marine, estuarine, and freshwater systems. Some species include human and animal pathogens capable of causing gastroenteritis, wound infections, cholera, and fatal septicemia. Over the past decades, cutting edge research on Vibrio genomics has promoted a tremendous advance in our knowledge of these pathogens. Significant developments include the discovery of emerging epidemic clones, tracking the spread of new strain variants, and an intensified appreciation of the role of mobile genetic elements in antibiotic resistance spread as well as pathogenesis. Furthermore, improved understanding of the interaction of Vibrios with a variety of living organisms in the aquatic environment has documented the significant role of environmental reservoirs in their seasonal cycle favoring persistence of the pathogen during inter-epidemic periods and enhancing disease transmission. This Research Topic is dedicated to our current understanding in these areas and will bring together leading experts in the field to provide a deep overview of Vibrios ecology and evolution, and will suggest the pathway of future research in this field.
