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Sex Hormones in Neurodegenerative Processes and Diseases
The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
Bases científicas de la drogadicción
La última década ha sido el escenario de un avance arrollador en el conocimiento de las bases científicas de la drogadicción. Este libro sistematiza e integra esa gran cantidad de información para facilitar su comprensión pública y sus usos en los programas de prevención y tratamiento. Los nuevos avances que se abordan en este libro explican cómo el abuso de la drogas modifica las regiones del cerebro asociadas al placer y la motivación. Ayudan también a entender cómo el uso recreacional de las mismas pude llevar a la drogadicción, enfermedad crónica del cerebro caracterizada por el uso compulsivo de substancias con una alta tasa de recaídas. Asimismo, se analizan los efectos de las drogas adictivas a nivel celular y molecular, que son la base de las modernas estrategias farmacológicas para el manejo clínico del adicto.
Guía Silber
None
Drugs, Addiction, and the Brain
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction
Familie, Ehre und Macht
Die Studie stellt die erste systematische Untersuchung zum kolonialspanischen Adel dar. In der Tradition der modernen sozialgeschichtlichen Erforschung regionaler Adelsgruppen des fruehneuzeitlichen Europa verbindet die Studie die Herausarbeitung der rechtlich-institutionellen Grundlagen und des zeitgen�ssischen kolonialspanischen Adelskonzeptes mit der prosopographischen Analyse der bedeutendsten Adelsfamilien der untersuchten Stadt und Region. Die vorliegenden Ergebnisse bieten damit weiterhin entscheidende Aufschluesse ueber die Grundlagen der sozialen Schichtung und Mentalit�t in dieser Region des spanischen Kolonialreiches am Vorabend der Unabh�ngigkeit und erhellen gleichzeitig zentrale Elemente des kolonialen Erbes in der Geschichte des unabh�ngigen Staates Ecuador.
Upholding Justice
Explores the close relationship between judicial institutions and the social fabric of early modern Quito
The Diary of Heinrich Witt (10 vols.)
The diary of Heinrich Witt (1799-1892) is the most extensive private diary written in Latin America known to us today. Written in English by a German migrant who lived in Lima, it is a unique source for the history of Peru, and for international trade and migration.
