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A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations
The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and...
A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems
The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and...
Synthetic Biology - A Primer (Revised Edition)
Synthetic Biology — A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelli...
Synthetic Biology - a Primer (revised Edition)
Synthetic Biology -- A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modellin...
Current Trends in Nonlinear Systems and Control
This volume is an outgrowth of the workshop "Applications of Advanced Control Theory to Robotics and Automation, "organized in honor of the 70th birthdays of Petar V. Kokotovic and Salvatore (Turi) Nicosia. Both Petar and Turi have carried out distinguished work in the control community and have long been recognized as mentors, as well as experts and pioneers in the field of automatic control, covering many topics in control theory and several different applications. The variety of their research is reflected in this book, which includes contributions ranging from mathematics to laboratory experiments. The scope of the work is very broad, and although each chapter is self-contained, the book has been organized into thematically related chapters, which in some cases, suggest to the reader a convenient reading sequence. The great variety of topics covered and the almost tutorial writing style used by many of the authors will make this book suitable for both experts in the control field and young researchers who seek a more intuitive understanding of these relevant topics in the field.
Our Transgenic Future
"Genetic modification, especially in regards to the creation of transgenic animals, has long been a source of controversy, fear, and fascination. Our Transgenic Future explores the creation, the ethical ramifications, and the symbolic resonances of one particular transgenic invention: a goat that creates spider silk. Lisa Jean Moore's new work draws from years of ethnographic research as well as her personal experiences with genetic engineering in the form of reproduction through artificial insemination. Her book provides an in depth look at the birth of the spider goat, chronicling its creation chapter by chapter. However, the animal is constantly connected to a variety of larger themes, including humanity's reciprocal interaction with nature, the figure of the "mad scientist," and the experience of aging and obsolescence"--
Reinforcement Learning and Dynamic Programming Using Function Approximators
From household appliances to applications in robotics, engineered systems involving complex dynamics can only be as effective as the algorithms that control them. While Dynamic Programming (DP) has provided researchers with a way to optimally solve decision and control problems involving complex dynamic systems, its practical value was limited by algorithms that lacked the capacity to scale up to realistic problems. However, in recent years, dramatic developments in Reinforcement Learning (RL), the model-free counterpart of DP, changed our understanding of what is possible. Those developments led to the creation of reliable methods that can be applied even when a mathematical model of the sy...
The Koopman Operator in Systems and Control
This book provides a broad overview of state-of-the-art research at the intersection of the Koopman operator theory and control theory. It also reviews novel theoretical results obtained and efficient numerical methods developed within the framework of Koopman operator theory. The contributions discuss the latest findings and techniques in several areas of control theory, including model predictive control, optimal control, observer design, systems identification and structural analysis of controlled systems, addressing both theoretical and numerical aspects and presenting open research directions, as well as detailed numerical schemes and data-driven methods. Each contribution addresses a s...
The Antisocial Mind
In this book, Professor Ghahreman Khodadad illuminates the basis of human behavior by examining the structures that underline antisociality. The book’s central thesis is that antisocial people are so thanks to biological and neurological structures. The principle of structure to function is used to argue that the brain, without us being conscious of it, produces our behaviors. If this claim is correct, then antisocial individuals are not accountable for their antisocial behavior, and they should be treated respectfully instead of being punished. Furthermore, prisons should accordingly be converted into rehabilitation, treatment, and behavioral research centers. This is a book for the general reader who is interested in the basis of human behavior. It should also be of interest to psychologists, psychiatrists, neuroscientists, geneticists, neurobiologists, and philosophers.
A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations
The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and...
