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Characterization and Clinical Management of Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis and uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the western world. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, severa...
Enzymology and Molecular Biology of Carbonyl Metabolism 13
The continuation of an annual series, Enzymology and Molecular Biology of Carbonyl Metabolism is the largest collection of articles on the three major gene families. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. It is an important reference for researchers in toxicology and molecular biology.
HIV-Associated Neurocognitive Disorders
HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection. - Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities - Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms - Examines animal models for studying HAND, including macaque and rodent models - Presents insights into epigenetic regulation and signaling pathways implicated in HAND - Covers prevention, therapeutic strategies, and diagnostic approaches
Advances in Emerging Solar Cells
Photovoltaic (PV) cells, which directly convert sunlight into electricity, are renewable sources of energy that are sustainable and totally inexhaustible. Emerging classes of solar PV cells have drawn considerable attention because they provide significant advantages over traditional silicon solar cells, such as low cost and attractive designs (lightweight, flexible, and portable) while exhibiting promising performance. Despite these features, certain challenges restrict the possible commercialization of these technologies. The world's leading scientists are making numerous efforts focused on bringing these promising technologies closer to commercialization. Some of these scientists provided...
Complications in Dialysis
The book surveys common complications in the procedure of dialysis, including those due to inherent complexities related to advanced kidney disease and the disorders that cause it. The chapters review the pathophysiology or mechanisms of each complication, how it can be recognized and managed, and more importantly how it can be prevented. The text also addresses whether the complication is due to conditions associated with kidney disease, such as frailty and muscle weakness, or whether the complication occurs as the consequence of treatment. The complications addressed include infections, AV access and catheter issues, problems in procedure, coagulation-related disorders, and falls, among others. Written by experienced dialysis experts, this book is a resource and learning tool for anyone involved in caring for patients undergoing renal replacement therapy.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
