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The Somatotrophic Axis in Brain Function
The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression.This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on loca...
JAMA
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Hesburgh
The most versatile and highly respected academic leader in the United States, Father Theodore Hesburgh was known for his rare energy and ability to carry out a staggering variety of assignments with distinction. He combined an exceptional blend and balance of qualities-intellect, character, personality, spirituality, and management skill. A man of enormous good will, he tried to embody the compassion of Christ. During his career as president of the University of Notre Dame from 1952 to 1987, enrollment doubled, the endowment grew from $9 million to $350 million, and the number of buildings on campus increased from 48 to 88. At the time of his retirement, his signature was on the degrees of f...
