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Corynebacterium glutamicum
Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
Industrial Application of Immobilized Biocatalysts
Offers practical examples of bioreactor systems that use immobilized biocatalysts - including enzymes and microbial cells - that have been implemented on the industrial level in Japan and Denmark. The book provides information on the current status of successful new bioreactor technologies.
Biorefineries
Biorefineries outlines the processes and steps to successfully scale up production of two types of biofuels, butanol and ethanol, from cellulosic residues for commercial purposes. It covers practical topics, including biomass availability, pretreatment, fermentation, and water recycling, as well as policy and economic factors. This reflects the unique expertise of the editor team, whose backgrounds range from wood and herbaceous feedstocks to process economics and industrial expertise. The strategies presented in this book help readers to design integrated and efficient processes to reduce the cost of production and achieve an economically viable end product - Outlines the economic benefits of designing a single operational process. - Includes all currently available processes on pretreatment, fermentation and recovery - Covers all pretreatment, fermentation, and product recovery options - Focuses on biofuels but acts as a stepping stone to develop cost-efficient processes for an array of commodity chemicals
Amino Acid Fermentation
This book presents the latest findings on amino acid fermentation and reviews the 50-year history of their development. The book is divided into four parts, the first of which presents a review of amino acid fermentation, past and present. The second part highlights selected examples of amino acid fermentation in more detail, while the third focuses on recent advanced technologies. The last part introduces readers to several topics for future research directions in amino acid production systems. A new field, “amino acid fermentation”, was created by the progress of academic research and industrial development. In 1908, the Japanese researcher Kikunae Ikeda discovered glutamate as an Umam...
Genomic Adaptation for Organohalide Respiration of Vinyl Chloride and Other Priority Pollutants by the Anaerobic Bacterium Dehalococcoides
Vinyl chloride (VC) is a widespread groundwater pollutant and Group 1 carcinogen. Microbial respiration of VC is both critical for complete remediation of chloroethenes in situ, and a unique physiology only observed by certain strains of Dehalococcoides. Two different genes independently encoding VC respiration in Dehalococcoides, vcrA and bvcA, were identified previously, each a member of the diverse family of reductive dehalogenase homologous genes, or rdhA. In this thesis I report that vcrA and bvcA are among a subset of putative 'foreign' rdhA with a low GC3 codon usage that favors the nucleotide T, even though tRNAs recognizing T-ending codons are categorically absent in Dehalococcoides...
D-Xylitol
Commercially, D-xylitol is produced by chemical reactions that are tailored to the requirements of various sectors. However, due to the rising interest in sustainable development and ecologically benign practices, microbial transformation processes are generally preferred over the conventional chemical conversion process. The former have multiple advantages, including less chemical load on the environment, higher efficiency, and the ability to dilute multiple downstream transformation attempts while maintaining product yield and recovery. This book aims to disseminate the most current advances in the biotechnological production of D-xylitol and its applications in medical and health care. It...
Climate Change and Circular Economics
Climate Change and Circular Economics: Human Society as a Closed Thermodynamic System aims to go beyond the concept of 'fighting climate change' to analyze the capacity of human society to evolve in relation to the environment based on a more complex approach. The book stresses the role of resource recovery by innovation in reducing the temperature increase, determined through an irreversible thermodynamic approach. Determining the speed of temperature increase contributed by selected economies and comparing these to environmental recovery time constants shows that emerging economies have a much greater speed and consequently a larger impact on environmental capability to recover.Chapters pr...
Sustainable Butanol Biofuels
Bio-butanol has gained wide recognition globally as an advanced biofuel, which can be used directly as a substitute for gasoline in internal combustion engines. This book provides readers with an in-depth knowledge of the various aspects and steps involved in butanol production. Further, the current global status, history, various technologies adopted for butanol production from different feedstocks, and the role of microorganisms in the production process are also covered. The book has 12 chapters, with each chapter dedicated to covering various aspects of butanol, from production to applications.
BioProducts
The book is focused on Bio Products derived from renewable resources processed by conventional catalytic thermochemical processes and or emerging bioprocessing techniques including fermentation and synthetic biology. It highlights some of these developments—from discovery, lab feasibility, scale up and eventual commercialization of interest and value in all the major sectors of the economy.
