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Advances in the Biology, Imaging and Therapies for Glioblastoma
This book is intended for physicians and scientists with interest in glioblastoma biology, imaging and therapy. Select topics in DNA repair are presented here to demonstrate novel paradigms as they relate to therapeutic strategies. The book should serve as a supplementary text in courses and seminars as well as a general reference.
Comprehensive Toxicology
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Helicobacter pylori and Gastric Cancer
This volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed. Helicobacter pylori is an extremely successful p...
Applied Three-Dimensional Subsurface Geological Mapping
The Gold-Standard “Bible” for Applied Subsurface Geological Mapping: Extensively Updated for Working Teams’ Latest Advances Long recognized as the most authoritative, practical, and comprehensive guide to structural mapping methods, Applied Three-Dimensional Subsurface Geological Mapping, Third Edition, has been thoroughly updated to reflect recent technical developments, with an emphasis on shale play basins, horizontal drilling, unconventional resources, and modern workflows. The authors of this edition have more than a century of collective experience in hydrocarbon exploration and development, in major, large, independent companies throughout the world. In this long-awaited update,...
ICO20
Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.
Critical Views of Logic
This book examines positions that challenge the Fregean logic-first view. It raises critical questions about logic by examining various ways in which logic may be entangled with mathematics and metaphysics. Is logic topic-neutral and general? Can we take the application of logic for granted? This book suggests that we should not be dogmatic about logic but ask similar critical questions about logic as those Kant raised about metaphysics and mathematics. It challenges the Fregean logic-first view according to which logic is fundamental and hence independent of any extra-logical considerations. Whereas Quine assimilated logic and mathematics to the theoretical parts of empirical science, the p...
The Routledge Handbook of the Philosophy of Evidence
What one can know depends on one’s evidence. Good scientific theories are supported by evidence. Our experiences provide us with evidence. Any sort of inquiry involves the seeking of evidence. It is irrational to believe contrary to your evidence. For these reasons and more, evidence is one of the most fundamental notions in the field of epistemology and is emerging as a crucial topic across academic disciplines. The Routledge Handbook of the Philosophy of Evidence is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first major volume of its kind. Comprising forty chapters by an international team of contributors the handbook is divided into six clear parts: The Nature of Evidence Evidence and Probability The Social Epistemology of Evidence Sources of Evidence Evidence and Justification Evidence in the Disciplines The Routledge Handbook of the Philosophy of Evidence is essential reading for students and researchers in philosophy of science and epistemology, and will also be of interest to those in related disciplines across the humanities and social sciences, such as law, religion, and history.
Towards Non-being
Graham Priest presents an account of the semantics of intentional language, which proceeds in terms of objects that may be either existent or non-existent, at worlds that may be either possible or impossible. This updated second edition includes ten new chapters which develop the ideas of the first edition, explore new areas, and reply to critics.
Exploring Cancer Metabolic Reprogramming through Molecular Imaging
The inclusion of oncogene-driven reprogramming of energy metabolism within the list of cancer hallmarks (Hanahan and Weinberg, Cell 2000, 2011) has provided major impetus to further investigate the existence of a much wider metabolic rewiring in cancer cells, which not only includes deregulated cellular bioenergetics, but also encompasses multiple links with a more comprehensive network of altered biochemical pathways. This network is currently held responsible for redirecting carbon and phosphorus fluxes through the biosynthesis of nucleotides, amino acids, lipids and phospholipids and for the production of second messengers essential to cancer cells growth, survival and invasiveness in the...
