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Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which severely affects the quality of life and survival of patients. The latest data from the International Diabetes Federation showed that there are approximately 537 million diabetic patients globally in 2021, and it is expected to reach 783 million by 2045. The treatment regime of diabetic patients mainly refers to the management of blood glucose and its complications. At present, typical hypoglycemic medications include insulin and non-insulin hypoglycemic drugs, which can be subdivided into a-glucosidase inhibitors, metformin, thiazolidinediones, sulfonylureas, glinides, DPP-4i, GLP-1RA, and...
Founded in 1971, the Academy of Marketing Science is an international organization dedicated to promoting timely explorations of phenomena related to the science of marketing in theory, research, and practice. Among its services to members and the community at large, the Academy offers conferences, congresses and symposia that attract delegates from around the world. Presentations from these events are published in this Proceedings series, which offers a comprehensive archive of volumes reflecting the evolution of the field. Volumes deliver cutting-edge research and insights, complimenting the Academy’s flagship journals, the Journal of the Academy of Marketing Science (JAMS) and AMS Review. Volumes are edited by leading scholars and practitioners across a wide range of subject areas in marketing science. This volume includes the full proceedings from the 2012 Academy of Marketing Science (AMS) Annual Conference held in New Orleans, Louisiana, entitled Marketing Dynamism & Sustainability: Things Change, Things Stay the Same.
This book gathers outstanding papers presented at the 16th Annual Conference of China Electrotechnical Society, organized by China Electrotechnical Society (CES), held in Beijing, China, from September 24 to 26, 2021. It covers topics such as electrical technology, power systems, electromagnetic emission technology, and electrical equipment. It introduces the innovative solutions that combine ideas from multiple disciplines. The book is very much helpful and useful for the researchers, engineers, practitioners, research students, and interested readers.
Anthropogenic climate change has driven widespread changes in marine environments, including ocean warming, ocean acidification, and the formation of hypoxic zones. Such environmental changes would pose direct challenges to the survival and adaptation of aquatic organisms, greatly affecting the biodiversity of marine life and marine ecosystems. Changes in the marine environment are likely to have strong effects at the physiological, behavioral, and molecular levels, with implications at the individual, population, and species levels, resulting in the degradation of genetic resources through massive mortality. For example, the ingestion, digestion, respiration, and growth of aquatic animals were greatly depressed under extreme environments. In the long run, maintaining a sustainable ocean would require a better understanding of the adaptation of marine animals in response to the effects of multiple environmental stressors. The Research Topic is aimed to discuss the potential impacts of individual and compounded extreme environments on aquatic animals, as well as the regulatory mechanisms and adaptation strategies of marine species to cope with these impacts.
In the past 20 years protein engineering has been used for the production of proteins mostly for biological applications. The incorporation of artificial amino acids and chemical handles into proteins had made possible the design and production of protein-based materials like hybrid inorganic-organic materials, smart/ responsive materials, monodisperse polymers, and nanoscale assemblies. In the current topic, we cover current uses and envision future applications of materials generated using protein engineering and biosynthesis techniques. I would like to acknowledge the U.S. Office of Naval Research for financial support and Dr. Cherise Bernard for her contributions during the early stages of the Research Topic.
This volume contains the proceedings of the 10th International Conference on Tools and Algorithms for the Construction and Analysis of Systems (TACAS 2004). TACAS 2004 took place in Barcelona, Spain, from March 29th to April 2nd, as part of the 7th European Joint Conferences on Theory and Practice of Software (ETAPS 2004), whose aims, organization, and history are detailed in a foreword by the ETAPS Steering Committee Chair, Jos ́ e Luiz Fiadeiro. TACAS is a forum for researchers, developers, and users interested in ri- rously based tools for the construction and analysis of systems. The conference serves to bridge the gaps between di?erent communities including, but not - mited to, those d...
The papers included in this issue of ECS Transactions were originally presented in the symposium ¿Industrial Electrochemistry and Electrochemical Engineering General Session¿, held during the 217th meeting of The Electrochemical Society, in Vancouver, Canada, from April 25 to 30, 2010.
The harshness of the modern Communist regime has far exceeded that of all past despots, as the PRC’s founder Mao Zedong openly acknowledged: “What was Emperor Qin Shi Huang? He only buried 460 scholars, but we buried 46,000. During the suppression of counter-revolutionaries, didn’t we kill some counterrevolutionary intellectuals? I’ve discussed this with pro-democracy advocates: ‘You call us Qin Shi Huang as an insult, but we’ve surpassed Qin Shi Huang a hundred-fold.’ Some people curse us as dictators like Qin Shi Huang. We must categorically accept this as factually accurate. Unfortunately, you haven’t said enough and leave it to us to say the rest”. In fact, the number o...
Comparison is a powerful cognitive research tool in science since it does 'across studies' to evaluate similarities and differences, e.g. across taxa or diseases. This book deals with comparative research on plant disease epidemics. Comparisons are done in specifically designed experiments or with posterior analyses. From the apparently unlimited diversity of epidemics of hundreds of diseases, comparative epidemiology may eventually extract a number of basic types. These findings are very important to crop protection. Plant disease epidemiology, being the ecological branch of plant pathology, may also be of value to ecologists, but also epidemiologists in the areas of animal or human diseases may find interesting results, applicable to their areas of research.
Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry, electrochemical detection, and microfluidics.