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After Dolly
Scientist Ian Wilmut describes the process by which he and other researchers at Scotland's Roslin Institute cloned the first mammal, a sheep named Dolly, and makes a case for the medical uses of cloning.
The Second Creation
The cloning of Dolly in 1996 from the cell of an adult sheep was a pivotal moment in history. For the first time, a team of scientists, led by Ian Wilmut and Keith Campbell, was able to clone a whole mammal using a single cultured adult body cell, a breakthrough that revolutionized three technologies--genetic engineering, genomics, and cloning by nuclear transfer from adult cells—and brought science ever closer to the possibility of human cloning. In this definitive account, the scientists who accomplished this stunning feat explain their hypotheses and experiments, their conclusions, and the ethical and scientific ramifications of their work. Written with award-winning science writer Colin Tudge, The Second Creation is a landmark work that details the most exciting and challenging scientific discovery of the twentieth century.
Principles of Cloning
Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning techni...
Essentials of Stem Cell Biology
First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, me...
The Cloning Sourcebook
Animal cloning has developed quickly since the birth of Dolly the sheep. Yet many of the first questions to be raised still need to be answered. What do Dolly and her fellow mouse, cow, pig, goat and monkey clones mean for science? And for society? Why do so many people respond so fearfully to cloning? What are the ethical issues raised by cloning animals, and in the future, humans? How are the makers of public policy coping with the stunning fact that an entire animal can be reconstructed from a single adult cell? And that humans might well be next? The Cloning Source Book addresses all of these questions in a way that is unique in the cloning literature, by grounding what is effectively an...
After Dolly
This book provides a timely and important discussion of the potential value of cloning and of the ethical choices that this radical new technology has raised, including the issues surrounding the current status of stem-cell research. As leader of the team that produced Dolly, the first animal to be cloned from an adult cell, Ian Wilmut has played a unique role both in the science of cloning and the ensuing international debate about its implications. He has testifed before parliamentary and congressional committees in the UK, France and the US and given many public lectures on the subject, in addtion to participating in numerous panel discussions on the uses of cloning. AFTER DOLLY: THE USES AND MISUSES OF HUMAN CLONING distils the essence of the current scientific and social policy discussions around these critically important issues and presents them in an understandable manner so the educated reader can have an informed opinion.
Stem Cells
The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our underst...
The Ethics of Human Cloning
Today biological science is rising on a wall of worry. No other science has advanced more dramatically during the past several decades or yielded so many palpable improvements in human welfare. Yet, none except nuclear physics has aroused greater apprehensions among the general public and leaders in such diverse fields as religion, the humanities, and government. In this engaging book, Leon R. Kass, the noted teacher, scientist, humanist, and chairman of the President's Council on Bioethics, and James Q. Wilson, the preeminent political scientist to whom four United States presidents have turned for advice on crime, drug abuse, education, and other crises in American life, explore the ethics...
Who's Afraid of Human Cloning?
Gregory Pence offers a candid look at the arguments for and against human cloning.
Scientific and Medical Aspects of Human Reproductive Cloning
Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
