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Bioethics and the Future of Stem Cell Research
Despite years of heated social controversy over the use of human embryos in embryonic stem cell research, the caravan of stem cell science continues to proceed at an unrelenting pace all around the world. Bioethics and the Future of Stem Cell Research urges readers to look beyond the embryo debate to a much wider array of ethical issues in basic stem cell science and clinical translational research, including research involving adult and induced pluripotent stem cells. Insoo Hyun offers valuable insights into complex ethical issues ranging from pre-clinical animal studies to clinical trials and stem cell tourism, all presented through a unique blend of philosophy, literature and the history of science, as well as with Dr Hyun's extensive practical experiences in international stem cell policy formation. This thoughtful book is an indispensable resource for anyone interested in the science of stem cells and the practical and philosophical elements of research ethics.
Chimera Research
This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanti...
Brain Organoids in Research and Therapy
This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes. The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios. A...
Juridification in Bioethics
What is 'legal' about bioethics? What are the ideas and artefacts that bioethics encompasses, and how are they related to law? What is the role of law in bioethics? In this work, Calvin Ho attempts to address these questions in the context of the governance of human pluripotent stem cell research. In essence, he argues that the hybridization of law, through processes, devices and techniques of juridification, has helped to constitute bioethics as a public sphere and an emergent civic epistemology. Drawing on his multi-sited ethnographic fieldwork and on Actor-Network-Theory, Ho explains how the law has, through bioethics, contributed to the scientific and public understanding of human plurip...
Patients with Passports
The world may be getting smaller every day, but until very recently health care remained local. 'Patients with Passports' is the first comprehensive legal and ethical analysis of one part of the globalization of health care: medical tourism. The author examines the two sides of the industry: medical tourism for services legal in the patient's home country where patients travel to places such as India, Thailand and Mexico to reduce costs, avoid queues, or qualify for insurance incentives, and medical tourism for services illegal in the home country.
Biofabrication
How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with biology in the same way we build with synthetic materials. In this volume in the MIT Press Essential Knowledge series, Ritu Raman offers an accessible introduction to biofabrication, arguing tha...
Global Bodies in Grey Zones
Global Bodies in Grey Zones departs from the current globalised market in biological material and treatments. Three different forms of medical travel are in focus: transplant travel, fertility travel and stem cell travel. The global travelling includes legally organised cross-border care, as well as completely illegal activities involving trafficking in bodies and body parts implicating a range of people, technologies and treatments. The theoretical focus is grey zones ? various places where people, money, bodies, and so on constitute components in an international market. The authors are researchers from the cultural, social and medical sciences. They examine how people?s desperation, hopes and longing for health and reproduction fuel the travels.
The California Institute for Regenerative Medicine
The California Institute for Regenerative Medicine (CIRM) was created in 2005 by The California Stem Cell Research and Cures Act (Proposition 71) to distribute $3 billion in state funds for stem cell research. The passage of Proposition 71 by the voters of California occurred at a time when federal funding for research involving human embryonic stem cells was uncertain, given the ethical questions raised by such research. During its initial period of operations, CIRM has successfully and thoughtfully provided more than $1.3 billion in awards to 59 California institutions, consistent with its stated mission. As it transitions to a broadened portfolio of grants to stimulate progress toward its...
Handbook of Bioethical Decisions. Volume I
The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this work seeks to engender dense ethical epistemology scientis...
The Globalization of Health Care
The Globalization of Health Care is the first book to offer a comprehensive legal and ethical analysis of the most interesting and broadest reaching development in health care of the last twenty years: its globalization. It ties together the manifestation of this globalization in four related subject areas - medical tourism, medical migration (the physician "brain drain"), telemedicine, and pharmaceutical research and development, and integrates them in a philosophical discussion of issues of justice and equity relating to the globalization of health care. The time for such an examination is right. Medical tourism and telemedicine are growing multi-billion-dollar industries affecting large n...
