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A lo largo de cinco capítulos, un total de quince autores y autoras repasan, desde el ámbito académico (Universidad de Navarra y Universidad de Barcelona) y social (Federación de Asociaciones Gitanas de Gaz Kaló y Fundación Secretariado Gitano), algunos de los retos a los que se enfrenta la juventud gitana en el entorno escolar y social. A partir de ahí se describen cuestiones para deshacer y rehacer, siempre desde una mirada inclusiva y basada en evidencias, proponiendo líneas de trabajo y mostrando experiencias reales exitosas.
Generations of Basques in New York have vibrantly exercised their culture, language, values, and traditions, transmitting to their children a robust sense of ethnic identity. In today's world of globalization it is often assumed that particular communities are disappearing as a consequence of the factors of homogenization. However, the Basques have proved this false. Depicting Basque mutual aid societies, language courses, musical and dance troupes, cuisine classes, community activities, sport, political involvement, and ties to homeland institutions are just a few of the ingredients which mix to compose the chapters of this work. Readers will learn about the history and reasons why Basques ...
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The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.