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Computational Systems Biology
Computational Systems Biology: Inference and Modelling provides an introduction to, and overview of, network analysis inference approaches which form the backbone of the model of the complex behavior of biological systems. This book addresses the challenge to integrate highly diverse quantitative approaches into a unified framework by highlighting the relationships existing among network analysis, inference, and modeling. The chapters are light in jargon and technical detail so as to make them accessible to the non-specialist reader. The book is addressed at the heterogeneous public of modelers, biologists, and computer scientists. Provides a unified presentation of network inference, analysis, and modeling Explores the connection between math and systems biology, providing a framework to learn to analyze, infer, simulate, and modulate the behavior of complex biological systems Includes chapters in modular format for learning the basics quickly and in the context of questions posed by systems biology Offers a direct style and flexible formalism all through the exposition of mathematical concepts and biological applications
Papers Relating to the Foreign Relations of the United States
Prior to 1870, the series was published under various names. From 1870 to 1947, the uniform title Papers Relating to the Foreign Relations of the United States was used. From 1947 to 1969, the name was changed to Foreign Relations of the United States: Diplomatic Papers. After that date, the current name was adopted.
Advances in Computational Biology
This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.
Spores and Spore Formers
Bacterial spore formers have been the focus of intense study for almost half a century centered primarily on Bacillus subtilis. This research has given us a detailed picture of the genetic, physiological and biochemical mechanisms that allow bacteria to survive harsh environmental conditions by forming highly robust spores. Although, many basic aspects of this process are now understood in great detail, bacterial sporulation still continues to be a highly attractive model for studying various cell processes at a molecular level. There are several reasons for such scientific interest. First, some of the complex steps in sporulation are not fully understood and/or only are only described by 'c...
Simulation Algorithms for Computational Systems Biology
This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies. This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.
Dependable Computing - EDDC-3
The idea of creating the European Dependable Computing Conference (EDCC) was born at the moment when the Iron Curtain fell. A group of enthusiasts, who were pre viously involved in research and teaching in the ?eld of fault tolerant computing in different European countries, agreed that there is no longer any point in keeping pre viously independent activities apart and created a steering committee which took the responsibility for preparing the EDCC calendar and appointing the chairs for the in dividual conferences. There is no single European or global professional organization that took over the responsibility for this conference, but there are three national in terest groups that sent de...
Modeling in Systems Biology
The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive o...
Applied Informatics
This book constitutes the thoroughly refereed papers of the Second International Conference on Applied Informatics, ICAI 2019, held in Madrid, Spain, in November 2019. The 37 full papers and one short paper were carefully reviewed and selected from 98 submissions. The papers are organized in topical sections on bioinformatics; data analysis; decision systems; health care information systems; IT Architectures; learning management systems; robotic autonomy; security services; socio-technical systems; software design engineering.
Advances in Case-Based Reasoning
The papers collected in this volume were presented at the 6th European C- ference on Case-Based Reasoning (ECCBR 2002) held at The Robert Gordon University in Aberdeen, UK. This conference followed a series of very succe- ful well-established biennial European workshops held in Trento, Italy (2000), Dublin, Ireland (1998), Lausanne, Switzerland (1996), and Paris, France (1994), after the initial workshop in Kaiserslautern, Germany (1993). These meetings have a history of attracting ?rst-class European and international researchers and practitioners in the years interleaving with the biennial international co- terpart ICCBR; the 4th ICCBR Conference was held in Vancouver, Canada in 2001. Proc...
