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The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field. Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems. The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter. *New material covers basal ganglia, cerebellum, prefrontal cortex, and fear conditioning*Additional information available on applied issues (i.e., degenerative disease, aging, and enhancement of memory)*Each chapter includes an outline to assist student understanding of challenging concepts*Four-color illustrations throughout
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The zebrafish is the most important fish model in developmental andgenetic analyses. This book contains 19 review articles covering abroad spectrum of topics, from development to genetic tools. Thecontents range from early development, the role of maternal factorsand gastrulation, to tissue differentiation and organogenesis, such asdevelopment of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm
This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug design. The last chapter focuses on the vital subject of pharmacokinetics and the great strides that have been made in this discipline during the past decade. All chapters provide an insight into the skills required of the modern medicinal chemist, in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems. *Presents the latest research in the field of drug discovery *Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
An authoritative treatise on the history of botanical studies and exploration in Angola. For any region, cataloging, interpreting, and understanding the history of botanical exploration and plant collecting, and the preserved specimens that were amassed as a result, are critically important for research and conservation. In this book, published in cooperation with the International Association for Plant Taxonomy, Estrela Figueiredo and Gideon F. Smith, both botanists with expertise in the taxonomy of African plants, provide the first comprehensive, contextualized account of plant collecting in Angola, a large country in south-tropical Africa. An essential book for anyone concerned with the biodiversity and history of Africa, this authoritative work offers insights into the lives, times, and endeavors of 358 collectors. In addition, the authors present analyses of the records that accompanied the collectors’ preserved specimens. Illustrated in color throughout, the book fills a large gap in the current knowledge of the botanical and exploration history of Africa.
The natural mission of Computational Science is to tackle all sorts of human problems and to work out intelligent automata aimed at alleviating the b- den of working out suitable tools for solving complex problems. For this reason ComputationalScience,thoughoriginatingfromtheneedtosolvethemostch- lenging problems in science and engineering (computational science is the key player in the ?ght to gain fundamental advances in astronomy, biology, che- stry, environmental science, physics and several other scienti?c and engineering disciplines) is increasingly turning its attention to all ?elds of human activity. In all activities, in fact, intensive computation, information handling, kn- ledge s...
The field of sketch-based interfaces and modeling (SBIM) is concerned with developing methods and techniques to enable users to interact with a computer through sketching - a simple, yet highly expressive medium. SBIM blends concepts from computer graphics, human-computer interaction, artificial intelligence, and machine learning. Recent improvements in hardware, coupled with new machine learning techniques for more accurate recognition, and more robust depth inferencing techniques for sketch-based modeling, have resulted in an explosion of both sketch-based interfaces and pen-based computing devices. Presenting the first coherent, unified overview of SBIM, this unique text/reference bridges...
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