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Onconephrology
This case based resource focuses on kidney disease in patients with cancer. Chapters cover the pathophysiology and management of specific kidney diseases in cancer patients, as well as the impact of chemotherapy, toxicity of organ and stem cell transplantation and other emerging therapies. Filling a significant knowledge gap in this burgeoning field, Onconephrology features the latest evidence and clinical approaches for the beginner or experienced practitioner.
Blood Purification in Intensive Care
In the last twenty years, critical care medicine has been established as a specialty with its own therapies and procedures, with significant implications for clinical nephrology regarding severe acute renal failure. This typically multi-factorial condition is today predominantly seen in intensive care units. The complex knowledge and skills necessary to handle it have resulted in a field called Critical Care Nephrology, where nephrologist and intensivist either work side by side or have formally acquired expertise and training in both specialties. Extracorporeal renal replacement therapies, although originally used to treat end-stage renal disease patients, rapidly gained importance for acut...
Biomarkers
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
Blood Purification in Intensive Care
In the last twenty years, critical care medicine has been established as a specialty with its own therapies and procedures, with significant implications for clinical nephrology regarding severe acute renal failure. This typically multi-factorial condition is today predominantly seen in intensive care units. The complex knowledge and skills necessary to handle it have resulted in a field called Critical Care Nephrology, where nephrologist and intensivist either work side by side or have formally acquired expertise and training in both specialties. Extracorporeal renal replacement therapies, although originally used to treat end-stage renal disease patients, rapidly gained importance for acut...
Regenerative Nephrology
Since the publication of the first edition of this book in 2010, an explosion of spectacular discoveries in the field of regeneration has compelled the current revisit of the field of Regenerative Nephrology. This second edition features subjects as diverse as age and gender influencing regenerative processes; mechanisms and pathways of premature cell senescence affecting kidney regeneration; the ways intrinsic regenerative processes can become subverted by noxious stressors eventuating in disease progression; novel mechanistic and engineering efforts to recreate functional kidney or its component parts; cell reprogramming and reconditioning as emerging tools of future regenerative efforts; ...
Acute Kidney Injury
Acute kidney injury is defined as an abrupt change in serum creatinine and/or urine output, and a majority of patients admitted to the ICU have some evidence of the disorder. Unfortunately, treatment for this complex syndrome is as yet lacking and understanding is limited. An interdisciplinary panel of experts has contributed to this volume, illuminating some of the fundamental and complex aspects of the disorder ranging from pathophysiology to treatment, from emerging biomarkers to genetic polymorphisms. Other contributions focus on immunological issues or the many complications of acute kidney injury and co-morbid conditions encountered, covering the fundamentals as well as the latest deve...
Therapy in Nephrology and Hypertension E-Book
Thoroughly revised, the new edition of this companion to Brenner & Rector’s The Kidney equips you with today’s guidance to effectively manage renal and hypertension patients. International authorities emphasize the specifics of treatment while presenting field-tested advice on the best therapeutic strategies available. New chapters reflect the latest evidence impacting current clinical issues, while a new design helps you reference the information more easily. Presents the most comprehensive text available on nephrology and hypertension treatment for a convenient single source that is easy to consult. Features the evidence-based guidance of leading authorities for making more informed cl...
Primer on Kidney Diseases E-Book
This official publication of the National Kidney Foundation (NKF) covers all aspects of adult and pediatric kidney diseases and is ideal for nephrologists and non-nephrologists alike. The full-color design, high-quality photographs, and outstanding graphs and tables make information easy to access and understand. The latest management techniques and pearls from leading clinical experts—including international contributors—offer practical and authoritative guidance. Edited by Dr. Arthur Greenberg and members of the NKF Scientific Advisory Board, this state-of-the-art primer provides consistent depth of coverage, balanced discussion of controversy, and a uniform focus of information. Incor...
Biomarkers in Renal Disease
Advances in long-term improvement and outcomes of patients with kidney disease will require the use of novel biomarkers to identify patients at high risk for kidney disease and to diagnose kidney disease early for effective treatment. A biomarker is a substance found in the blood, body fluids or tissues that provides a measure of normal biological or pathological processes or response to pharmacological compounds or drugs. There are a wide variety of biomarkers including but not limited to mRNA, proteins and peptides, and lipid molecules. In AKI, important pathophysiological processes such as inflammation, apoptotic and necrotic cell death and, tubule regeneration may be reflected in blood o...
Computational Intelligence Methods for Bioinformatics and Biostatistics
This book constitutes the thoroughly refereed post-conference proceedings of the Fifth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2008, held in Vietri sul Mare, Italy, in October 2008. The 23 revised full papers presented together with 3 invited lectures were carefully reviewed and selected from 69 submissions. The main goal of the CIBB meetings is to provide a forum open to researchers from different disciplines to present and discuss problems concerning computational techniques in bioinformatics, systems biology and medical informatics with a particular focus on neural networks, machine learning, fuzzy logic, and evolutionary computation methods.
