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This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
Examining current advances in nephrology based on recent progress in molecular and cellular biology, this unique reference-the first of its kind-defines kidney development, structure, function, and disease primarily from a molecular viewpoint.
The field of acute-care nephrology has recently seen significant changes, affecting the definition and classification of acute kidney dysfunction as well as our understanding of its epidemiology, the ability to make earlier diagnoses, the use of novel imaging modalities, and the insight into why acute kidney injury might occur under different clinical circumstances. Different experts have contributed to this issue, emphasizing the importance of the change of concept from that of acute renal failure to that of acute kidney injury. This change has led to the development of new definitions and classifications which, together with the understanding that even minor subclinical injury to the kidney may matter, emphasize the need to develop early biomarkers. Sufficiently early diagnosis, a better classification system and a clearer understanding of the pathogenesis promise to deliver novel and effective therapies for patients. Summarizing recent developments, this publication will be an indispensable help for the clinician to determine the best treatment options for his patients.
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
This case based resource focuses on kidney disease in patients with cancer. Chapters cover the pathophysiology and management of specific kidney diseases in cancer patients, as well as the impact of chemotherapy, toxicity of organ and stem cell transplantation and other emerging therapies. Filling a significant knowledge gap in this burgeoning field, Onconephrology features the latest evidence and clinical approaches for the beginner or experienced practitioner.
This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields o...
The ability to regulate cell volume in the face of osmotic challenge is one of the most fundamental of cellular homeostatic mechanisms. Cellular and Molecular Physiology of Cell Volume Regulation is an integrated collection of articles describing key aspects of cell volume control. The book has been organized around concepts and cellular/molecular processes rather than around mechanisms of volume regulation in specific cell types in order to make it more accessible to a multidisciplinary audience of students, instructors, and researchers.