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After a long career in science, which has involved a great deal of science writing for general audiences, Joseph V. Rodricks has turned out a powerful work of fiction. OFF TELEGRAPH takes the reader into a working laboratory and into the minds of working scientists. It also offers the reader a suspenseful story of deception and psychological disintegration, and of a brilliant young scientist's struggle to hold on to his ideals.PFAFFIDINE — a complex molecule from an exotic plant, with good potential as an anti-cancer drug. Will Getz's research project involves finding a way to synthesize pfaffidine in the lab.After many failed attempts to complete the synthesis, Will, in a moment of weakne...
In 1980, a group of scientists from national laboratories, universities, and other research organizations gathered informally in a series of meetings to consider the state of research on risks to health, safety, and the environment. Each scientist had conducted research on the subject. All felt that the traditional disciplines and professional societies to which they belonged were neither ade quate nor appropriate for addressing the extraordinarily complex problems of assessing the risks inherent in modern society. The con sensus of the group was that a new society was needed to address these problems in a scientific and objective way. From these initial meetings, the Society for Risk Analys...
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in ri...
For the last 150 years, chemicals have been tested on animals for the alleged purpose of protecting the public from their dangerous effects. Lethal Laws reveals that using animals as human surrogates is not only unethical, it is bad science. Alix Fano provides a meticulous analysis of the technical and scientific problems that have plagued animal tests for decades, but which have not been forcefully challenged until now. She shows how animal testing has been used as an alibi to allow the continued use of thousands of toxic chemicals. In a field dominated by male voices, this is a pioneering work by a woman that effectively demonstrates the causal link between animal testing and environmental degradation, and the subsequent deterioration of human health.
This book summarizes the authority of regulatory agencies and programs as they pertain to the cosmetic industry, offers practical advice on how to operate within the regulatory environment, and introduces scientific and regulatory issues that are likely to have an impact on cosmetic manufacturers. "This interesting volume reports all the novel technologies in use to study and control the cosmetic products in order to make them effective and free of side effects." ---Journal of Applied Cosmetology, 2000
The Reference Manual on Scientific Evidence, Third Edition, assists judges in managing cases involving complex scientific and technical evidence by describing the basic tenets of key scientific fields from which legal evidence is typically derived and by providing examples of cases in which that evidence has been used. First published in 1994 by the Federal Judicial Center, the Reference Manual on Scientific Evidence has been relied upon in the legal and academic communities and is often cited by various courts and others. Judges faced with disputes over the admissibility of scientific and technical evidence refer to the manual to help them better understand and evaluate the relevance, relia...
This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.