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Advanced Materials in Drug Release and Drug Delivery Systems
Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. ...
Paediatric Formulation
The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
Marine Polysaccharides Volume 3
This book is a printed edition of the Special Issue "Marine Polysaccharides" that was published in Marine Drugs
Polymeric Materials
This book collects the articles published in the Special Issue “Polymeric Materials: Surfaces, Interfaces and Bioapplications”. It shows the advances in polymeric materials, which have tremendous applications in agricultural films, food packaging, dental restoration, antimicrobial systems, and tissue engineering. These polymeric materials are presented as films, coatings, particles, fibers, hydrogels, or networks. The potential to modify and modulate their surfaces or their content by different techniques, such as click chemistry, ozonation, breath figures, wrinkle formation, or electrospray, are also explained, taking into account the relationship between the structure and properties in the final application. Moreover, new trends in the development of such materials are presented, using more environmental friendly and safe methods, which, at the same time, have a high impact on our society.
Advances in Phytonanotechnology for Treatment of Various Diseases
Several plant bioactives or plant-derived therapeutic molecules have been used against life-threatening diseases and their nanoparticle-mediated delivery greatly improves therapeutic efficacy. Advances in Phytonanotechnology for Treatment of Various Diseases aims to describe past and recent advances achieved in the field of phytonanotechnology. The chapters of this book provide thorough knowledge of medicinal plants, plant bioactives, plant extract-based nanoparticle synthesis, delivery of plant bioactives through nanoparticles, and their therapeutic activity against life-threatening diseases. This book focuses on the therapeutic activity of phytocomponents present in plants from diverse fam...
Last Judgment Iconography in the Carpathians
Few subjects in Christianity have inspired artists as much as the last judgment. Last Judgment Iconography in the Carpathians examines images of the last judgment from the fifteenth century to the present in the Carpathian mountain region of Ukraine, Poland, Slovakia, and Romania, as a way to consider history free from the traditional frameworks and narratives of nations. Over ten years, John-Paul Himka studied last-judgment images throughout the Carpathians and found a distinctive and transnational blending of Gothic, Byzantine, and Novgorodian art in the region. Piecing together the story of how these images were produced and how they developed, Himka traces their origins on linden boards ...
Ikony
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Kultura rocka 1. Twórcy, tematy, motywy
Stan badań na temat kultury rocka w polskim obszarze nauki jest jeszcze mało zaznaczony, jednak w ciągu kilkunastu ubiegłych lat można zauważyć wyraźną tendencję zwyżkową w tej dziedzinie. Na świecie, szczególnie w krajach anglosaskich, badania nad rockiem od wielu lat cieszą się niesłabnącą popularnością.
Marian Kruczek
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