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Pharmacogenetics and Individualized Therapy
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific disease areas, including cardiovascular, psychiatry, cancer, asthma/COPD, adverse drug reactions, transplantation, inflammatory bowel disease, and pain medication. Clinical practice and ethical issues make up the third section, with the fourth devoted to technologies like genotyping, genomics, and proteomics. In the fifth part, chapters discuss the impact of key regulatory issues on the pharmaceutical industry.
First Episode Psychosis
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.
Understanding Depression
Depression is a major cause of morbidity and a significant public health problem. This book brings together world leaders in research on depression to discuss both classical and innovative ideas for understanding this devastating disorder. It includes cutting edge research from neurobiology, psychology, genetics, and evolutionary biology.
Seminars in General Adult Psychiatry
This second edition of Seminars in General Adult Psychiatry provides a highly readable and comprehensive account of modern adult psychiatry. Key features of the first edition that have been retained are the detailed clinical descriptions of psychiatric disorders, and historical sections to give the reader access to the classic studies of psychiatry as well as the current evidence. Additional topics covered here for the first time include liaison psychiatry, psychosexual medicine, clinical epidemiology, and international and cultural psychiatry. Clinical management is given due prominence, with extensive accounts of modern drug management, cognitive therapy, the main psychosocial approaches, and current guidelines such as those published by the National Institute for Health and Care Excellence. An essential text for trainees studying for their MRCPsych, this book is also a one-stop reference work for established practitioners, providing comprehensive coverage of the whole of adult psychiatry.
Essential Psychiatry
This is a major international textbook for psychiatrists and other professionals working in the field of mental healthcare. With contributions from opinion-leaders from around the globe, this book will appeal to those in training as well as to those further along the career path seeking a comprehensive and up-to-date overview of effective clinical practice backed by research evidence. The book is divided into cohesive sections moving from coverage of the tools and skills of the trade, through descriptions of the major psychiatric disorders and on to consider special topics and issues surrounding service organization. The final important section provides a comprehensive review of treatments covering all of the major modalities. Previously established as the Essentials of Postgraduate Psychiatry, this new and completely revised edition is the only book to provide this depth and breadth of coverage in an accessible, yet authoritative manner.
Seminars in Clinical Psychopharmacology
Expanded from previous editions, and integrating basic science, psychopharmacology and clinical practice with up-to-date clinical guidelines.
Thrive
We live in a world that demands perfection. Should we not meet established milestones or targets, not conform to the appropriate curve, or fail to live up to pre-established societal expectations, we invariably experience a sense of personal failure, worthlessness, and fears and anxiety about a tenuous future. Added to this is the struggle with financial pressures and widening gaps in inequality, fractured family units, chronic stress and mental health challenges, overlaid with the uncertainty and complexity of a rapidly changing world. Yet, in truth, it doesn’t matter where we come from and what our historic circumstances and achievements might be. We are all capable of extraordinary live...
Biology of Depression
The first major reference to cover the clinical aspects of this common and complex disorder of unknown cause. Readers will also learn about current understanding of the psychosocial, environmental, biological, and genetic aspects of depression. The authors are internationally recognized experts from leading academic and industrial environments, and they present the features, advantages, and limitations of animal models while reviewing candidate biological systems and genetic approaches. In addition, the book covers the important topic of the medical consequences of depression, as clinicians and investigators increasingly appreciate how it negatively impacts on cardiovascular function and bone mineral density. Finally, a separate section is devoted to the biochemical and molecular basis for existing treatments, along with strategies for the use of genomic tools to discover new targets for antidepressants and to predict therapeutic outcomes.
The Breath of Empire
This Palgrave Pivot combines anthropological, biographical and autoethnographic perspectives onto imperial intimacies, the transgenerational transmission of colonial and familial trauma, and violence in two kinds of household: the Chinese family in British Hong Kong and wider imperial Asia, and the Anglo-Chinese family in England. Conjoining approaches from literary anthropology, the historiography of Anglo-Chinese relations, and perspectives on colonial trauma, it highlights the relative neglect of women’s stories in customary Chinese readings, colonial accounts, and an ancestral family record from 1800 to the present. Offering an alternative view of family history, this book links the body as a dwelling for assaults on the ability to breathe—through tuberculosis, opium smoking, asthma, and panic—with the physical home that is assaulted in turn by bombs, killing, intimate betrayals, and fatal respiratory illness. The COVID-19 “pandemic of breathlessness” serves as mnemonic both for state repression, and for the reprisal of historical fears of suffocation and dying. These phenomena converge under an analytic concept the author calls respiratory politics.
