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Hailed by Margaret Thatcher as the founder of modern conservatism, Keith Joseph is commonly ranked among the most influential politicians of the late-20th century. A complex and enigmatic figure Joseph was almost unique among Mrs Thatcher's senior ministers in refusing to write his own memoirs. Challenging both the "mad monk" view held by his critics and his status of mythical hero to his admirers, the authors present a picture of Joseph as a thinker and decision-maker. the authors tell of Joseph's formative years before he entered Parliamnet in 1956: the powerful Jewish dynasty into which Josph was born; his time at Harrow; at Oxford; his war years in the Royal Artillery; and his Fellowship at All Souls. This volume charts the political career of Keith Joseph. The authors challenge Joseph's self-declared conversion to Conservatism in 1974 and the importance of his "education" of Margaret Thatcher. His own ambition, intellectual integrity and consistency are all examined and a different picture emerges of his role as the intellectual driving force behind Conservative Government policy in the 1980s.
"Case: This 68-year-old right-handed man was evaluated after an episode of delirium. Three months prior, in the span of two days, he became confused and agitated. At the hospital, he was found to have a urinary tract infection (UTI). Within three days after treatment, he returned to his baseline cognitive function and remained stable since. Although he initially reported no cognitive problems, upon further questioning he acknowledged word-finding difficulties and forgetfulness for at least the previous 2 years. His daughter reported that he repeated questions and stories"--
This volume provides a comprehensive understanding of the biology of dementias, including information on advancements in the way these disorders are perceived and studied. From earlier assumptions that cognitive deficits were simply age related, this handbook progresses into complex discussions of the diseases that affect the cortex of the human brain. Clinicians will find extensive diagnostic and research perspectives on a variety of interesting topics, including neuropathology, physiopathology, biology, clinics, and imaging information on all, or most, of the dementing disorders currently known. In addition, chapters devoted to legal and ethical issues give practitioners and health care wo...
This book focuses on extrapyramidal signs and symptoms of all types of dementia, and addresses the issue of the artificial boundary between dementias and Parkinsonism, which represent the two most common symptoms found in degenerative central nervous system diseases. In Movement Disorders in Dementias, movement disorder specialists from around the world write on topics generally restricted to dementia experts. Important motor issues related to either medication in demented patients (drug-induced movement disorders) or manifestations common to all forms of dementia, regardless of underlying cause (gait disorders, falls, fear of falling), is followed by analysis of the relationship between motor and cognitive symptoms, from their common pathogenesis to specific medical treatments. Movement Disorders in Dementias is aimed at general neurologists, dementia specialists, movement disorders specialists, neuropsychologists and geriatricians.
This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.
Dementia is a devastating diagnosis for patients Dementia comes in many forms that can be hard to differentiate. Arriving at an accurate diagnosis without subjecting an already wary patient to unnecessary tests requires clinical acumen. Identifying the correct dementia, and determining a probable prognosis, allows agreement on appropriate management and care with patients and their carers. But how much testing is needed? What do the tests tell you? What management options are available? Dementia provides a progressive approach to help you identify and manage the many forms of this complex and devastating disease. Dr Quinn has assembled a team of expert neurologists and gerontologists to provide the foundation knowledge you need to develop the clinical wisdom for effective dementia care. Dementia clearly explains the diagnosis, investigations and management for Normal pressure hydrocephalus Mild cognitive impairment Alzheimer’s disease Vascular dementia Dementia with Lewy bodies Fronto-temporal dementia Clinical in approach, practical in execution, Dementia helps you diagnose and treat your patients more effectively.
This collection of 21 papers, selected from presentations internationally, reflect the depth and focus of Professor Shepherd's work over the past ten years, in the areas of conquest and colonialization, slavery and anti-slavery, post-slavery society, the project of decolonialization and the role of gender.
Frontotemporal Degeneration (FTD) is now recognized as one of the most common forms of dementia in individuals under age 65, second only to Alzheimer's. Shedding light on a little known brain disease, this volume examines FTD from a few angles, beginning with the author's insightful memoir of her husband's struggle with FTD and its impact on their family. Detailed background information on the disease is provided along with discussion of related issues, and information on how to minimize the chances of becoming a victim.
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.