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Synthetic Biology: A Lab Manual
Synthetic Biology: A Lab Manual is the first manual for laboratory work in the new and rapidly expanding field of synthetic biology. Aimed at non-specialists, it details protocols central to synthetic biology in both education and research. In addition, it provides all the information that teachers and students from high schools and tertiary institutions need for a colorful lab course in bacterial synthetic biology using chromoproteins and designer antisense RNAs. As a bonus, practical material is provided for students of the annual international Genetically Engineered Machine (iGEM) competition. The manual is based upon a highly successful course at Sweden's Uppsala University and is coauthored by one of the pioneers of synthetic biology and two bioengineering postgraduate students.An inspiring foreword is written by another pioneer in the field, Harvard's George Church: “Synthetic biology is to early recombinant DNA as a genome is to a gene. Is there anything that SynBio will not impact? There was no doubt that the field of SynBio needed ‘A Lab Manual’ such as the one that you now hold in your hands.”
Bios
Das Wild, das du jagst: Du bist es selbst Im Jahr 2045 ist das Zeitalter der Technik Geschichte; die biologische Moderne ist angebrochen. Algen und Pilze bauen Autogehäuse, die Boomstädte Asiens werden nachts von Leuchtbäumen erhellt. Auch vor dem menschlichen Körper macht die Bio-Revolution nicht halt. Jeder will hochgezüchtete Designer-Babys, ob legal oder nicht. Die Zeche zahlen andere. Kenneth Durand leitet bei Interpol den Kampf gegen diese Genkriminalität. Und ein Mann steht dabei im Fadenkreuz: Marcus Demang Wyckes, Kopf eines so mächtigen wie skrupellosen Kartells. Eines Tages erwacht Durand aus dem Koma. Man hat ihn entführt. Er sieht anders aus. Seine DNA ist verändert. Er ist Marcus Demang Wyckes. Der Mann, der weltweit gesucht wird.
Change Agent
New York Times bestselling author Daniel Suarez delivers an exhilarating sci-fi thriller exploring a potential future where CRISPR genetic editing allows the human species to control evolution itself. On a crowded train platform, Interpol agent Kenneth Durand feels the sting of a needle—and his transformation begins... In 2045 Kenneth Durand leads Interpol’s most effective team against genetic crime, hunting down black market labs that perform "vanity edits" on human embryos for a price. These illegal procedures augment embryos in ways that are rapidly accelerating human evolution—preying on human-trafficking victims to experiment and advance their technology. With the worlds of geneti...
BioBuilder
"[P]rovides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories"--Page [4] of book cover
Fine-Tuning of RNA Functions by Modification and Editing
Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored. This book provides advance information on RNA modification, including the associated editing m...
Zero to Genetic Engineering Hero
Zero to Genetic Engineering Hero is made to provide you with a first glimpse of the inner-workings of a cell. It further focuses on skill-building for genetic engineering and the Biology-as-a-Technology mindset (BAAT). This book is designed and written for hands-on learners who have little knowledge of biology or genetic engineering. This book focuses on the reader mastering the necessary skills of genetic engineering while learning about cells and how they function. The goal of this book is to take you from no prior biology and genetic engineering knowledge toward a basic understanding of how a cell functions, and how they are engineered, all while building the skills needed to do so.
Regenesis
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Introduction to Synthetic Biology
The textbook is based on the lectures of the course “Synthetic Biology” for Master’s students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT.
Activation and Catalytic Reactions of Saturated Hydrocarbons in the Presence of Metal Complexes
hemistry is the science about breaking and forming of bonds between atoms. One of the most important processes for organic chemistry is breaking bonds C–H, as well as C–C in various compounds, and primarily, in hydrocarbons. Among hydrocarbons, saturated hydrocarbons, alkanes (methane, ethane, propane, hexane etc. ), are especially attractive as substrates for chemical transformations. This is because, on the one hand, alkanes are the main constituents of oil and natural gas, and consequently are the principal feedstocks for chemical industry. On the other hand, these substances are known to be the less reactive organic compounds. Saturated hydrocarbons may be called the “noble gases o...
