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CRISPR
“An excellent compendium of all things CRISPR from some of the leading minds in the field. With thorough coverage from every angle and beautifully detailed illustrations, this book is not to be missed!” Jennifer A. Doudna, Professor of Chemistry, Biochemistry & Molecular Biology, UC Berkeley; Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of CRISPR technology “This journey through CRISPR biology and several of its breakthrough applications offers an exciting glimpse into one of the most beautiful and compelling fields in the life sciences.” David R. Liu, Director of the Merkin Institute at the Broad Institute of MIT and Harvard; Professor of Chemistry and Chemi...
Sortases, Transpeptidases that Anchor Proteins to the Envelope of Gram-positive Bacteria
The cell wall envelope of Gram-positive bacteria represents a surface organelle that functions not only as a cytoskeletal element for the physical integrity of microbes but also promotes interactions between bacteria and their environment. Most importantly for bacterial pathogens, as environments are subject to change, microbes respond with alterations in envelope structure and function. Bacterial cell wall assembly requires peptidoglycan precursors that together form a single large macromolecule, the murein sacculus, encircling the microbial cell with a 20-100 nm thick wall structure. Cell wall peptidoglycan is covalently and non-covalently decorated with teichoic acids, polysaccharides and...
Modern Prometheus
This book tells the dramatic story of Crispr and the potential impact of this gene-editing technology.
Molecular Biology and Pathogenicity of Mycoplasmas
was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather b...
The Economic Structure of Intellectual Property Law
This book takes a fresh look at the most dynamic area of American law today, comprising the fields of copyright, patent, trademark, trade secrecy, publicity rights, and misappropriation. Topics range from copyright in private letters to defensive patenting of business methods, from moral rights in the visual arts to the banking of trademarks, from the impact of the court of patent appeals to the management of Mickey Mouse. The history and political science of intellectual property law, the challenge of digitization, the many statutes and judge-made doctrines, and the interplay with antitrust principles are all examined. The treatment is both positive (oriented toward understanding the law as...
Cell Biology by the Numbers
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Bioelectrochemical Systems
In the context of wastewater treatment, Bioelectrochemical Systems (BESs) have gained considerable interest in the past few years, and several BES processes are on the brink of application to this area. This book, written by a large number of world experts in the different sub-topics, describes the different aspects and processes relevant to their development. Bioelectrochemical Systems (BESs) use micro-organisms to catalyze an oxidation and/or reduction reaction at an anodic and cathodic electrode respectively. Briefly, at an anode oxidation of organic and inorganic electron donors can occur. Prime examples of such electron donors are waste organics and sulfides. At the cathode, an electron...
Design and Analysis of Reliability Studies
Concerned with statistical problems of assessing the dependability, precision and bias of measurements. Using a practical approach, it features enough theoretical material enabling users of relevant techniques to understand why and how the vast array of concepts and methods can be applied. Coverage includes analysis of variance, linear regression and chi-square tests for two-way contingency tables.
