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Lysozyme
Lysozyme contains the proceedings of the Lysozyme Conference held in New York on October 29-31, 1972 on the occasion of the 50th anniversary of the discovery of lysozyme by Sir Alexander Fleming. The papers explore the chemistry and structure of lysozymes, their interactions with substrates and inhibitors, and distribution in tissues. Changes associated with various disease states are also discussed, along with evidence indicating that lysozyme may significantly alter certain mammalian cell constituents. Comprised of 42 chapters, this book begins with an overview of the structure of various lysozymes, including avian and mammalian lysozymes. The use of X-ray crystallography for lysozyme anal...
Lysozymes
Lysozymes are widely distributed in living organisms, and play an important role in self-defence by destroying the cell walls of pathogenic bacteria upon invasion. In this book, the authors present current research in the study of the sources, functions and role in disease of lysozymes. Topics include the adsorption behaviours of lysozyme adsorbed onto moderately hydrophobic surfaces; functional analysis using ESI-MS and NMR spectroscopy in the lysozyme superfamily; functions of lysozymes and identification by MALDI-MS; dissecting lysozyme by single-molecule techniques; the antimicrobial activity and allergenicity of hen egg white lysozymes; human lysozyme amyloid and protein folding; purifying lysozyme from egg whites; and growing hen egg-white lysozyme crystals for neutron experiments.
Human and Mosquito Lysozymes
Malaria remains an alarming emergency in developing countries. It is thus urgent to identify any parasite or host molecules that can serve as new affordable markers for early diagnosis of disease complications or as new targets for vector control. In this context, human and mosquito lysozymes are good candidate molecules, as their involvement in malaria has been recently reported by several independent groups. This book reviews the grounded knowledge on malaria etiology and physiopathology, as well as the current approaches for diagnosis, therapy, and vector control. In addition, the emerging evidence on the involvement of human and mosquito lysozymes in malaria from available experimental models and clinical studies is thoroughly discussed, as is the potential use of other antimicrobial peptides against malaria. Intriguingly, the contributors propose that old well-known molecules such as lysozymes might be used as new targets for cost-effective strategies to fight malaria.
Lysozyme
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Human Lysozyme
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