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Models of Viral Hepatitis
Viral hepatitis B or C is the most common cause of chronic liver disease worldwide and accounts for about 80% of all hepatocellular carcinoma cases. Thus, combating viral hepatitis remains one of the most pressing public health issues today. Animal models and cell-based systems are essential tools for addressing the many still unresolved basic and clinical problems. Experimental models are needed to better understand the viral life cycles, pathogenetic aspects and natural defense mechanisms, while preclinical models are required for evaluating novel preemptive and therapeutic strategies. This.
Viral Hepatitis
There has been an explosion of both the incidence and medicalknowledge of viral hepatitis over the last two decades. Not only isthe incidence of infection and disease increasing, but newhepatitis viruses have been discovered, as well as the launch ofnew pharmaceutical products. Previously published by Churchill Livingstone, ViralHepatitis by Zuckerman & Thomas was the first comprehensivebook on hepatitis and is recognized as the standardreference text in this field. The new third edition, now published by Blackwell Publishing,addresses the recent advances in diagnosis and treatment withentirely revised and current topics. It covers the entire spectrumof viral hepatitis and has something of interest for everyspecialist. Viral Hepatitis presents the latest thinking from theleading international researchers and clinicians working in thisfield and the Editors are joined by a North American co-Editor forthis edition - Professor Stanley Lemon of the University of Texas,Galveston, TX, USA. This book offers an ideal reference for all healthcareprofessionals involved in the research and patient care of thisdisease.
Brain Tumors
Analogue to the first edition, the principal characteristic of this work is its casting of pathology as the common nosographic link in the diagnosis, prognosis and treatment of brain tumours. A result of the author's many years of experience in the study of brain tumours and their pathological and clinical characteristics, the book presents different aspects of neurooncology from the perspective of pathology and its biological and clinical correlates. This new, second and enlarged volume preserves all the qualities of the first edition while further amplifying clinical applications and updating biological and pathological problems. The references have been completely revised and new chapters have been added on topics such as neuroimaging, invasion and angiogenesis. Professor Schiffer is President of the Italian Association of Neurooncology and of the Italian Association of Neuropathology.
New Concepts of Antiviral Therapy
Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.
Hepatitis Delta Virus
Hepatitis delta virus (HDV), which causes severe acute and chronic liver disease, was discovered nearly 30 years ago following the detection of a novel antigen-antibody system in hepatitis B virus carriers. HDV has continued to surprise and fascinate medical science ever since. This volume reviews recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.
Pediatric Infectious Diseases Revisited
Starting with historical, epidemiological and sociocultural issues, this book presents clinical and molecular biological aspects of pediatric infectious diseases. The text offers new insights into the pathogenesis of infection, and updates on diagnostics, prevention and treatment of pediatric viral, fungal and bacterial diseases, as well as emerging new pathogens. The book will interest an interdisciplinary audience of clinicians and non-clinicians: pediatricians, infectious disease researchers, virologists, microbiologists and more.
Manual of Clinical Microbiology
The most authoritative, comprehensive reference in the field. • Sets the standard for state-of-the-science laboratory practice. • A collaborative effort of 22 editors and more than 260 authors from around the world, all experienced researchers and practitioners in medical and diagnostic microbiology. • Includes 149 chapters of the latest research findings, infectious agents, methods, practices, and safety guidelines. • Indispensable to clinical microbiologists, laboratory technologists, and infectious disease specialists in hospitals, clinics, reference laboratories, and more
Pathology of the Human Placenta
Pathology of the Human Placenta remains the most comprehensive and authoritative text in the field. It provides extensive information on the normal placenta, encompassing physiology, metabolism, and endocrinology, and covers the full range of placental diseases in great detail. Further chapters are devoted to abortions, molar pregnancies, multiple pregnancies, and legal considerations. This sixth edition of the book has been extensively revised and expanded to reflect the most recent progress in the field, and a brand new chapter has been added on artificial reproductive technology. Some 800 illustrations are included, many of them in color. The detailed index has been further improved and tables updated. Pathology of the Human Placenta will be of enormous value to pathologists and obstetrician-gynecologists alike.
Viral Vectors in Veterinary Vaccine Development
This highly accessible textbook introduces readers to the development of viral vectors and discusses their application in veterinary vaccinology. It offers comprehensive information on the latest advances in this emerging research field, together with a broad overview of the history of veterinary vaccines and viral vectors. The book also addresses issues concerning funding, translational research and ethics that will impact the future development, manufacture and global use of viral vector-based veterinary vaccines. The book addresses the needs of graduate students and researchers in the fields of Veterinary Medicine, Virology and Immunology.
