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Inmunología de la piel
Esta segunda edición de Inmunología de la piel, responde a la necesidad de poner a dispocisión de colegas, estudiantes, médicos, pediatras, dermatólogos, inmunólogos clínicos y alergólogos, entre otros, un contenido actualizado, analítico y de calidad. Con los avances que en la actualidad nos ofrecen la ciencia, el conocimiento y la tecnología, los autores renovaron el contenido de los capítulos y, ahora, también se presentan otros temas como microbioma, cáncer e inmunomoduladores, todos estos, temas que ayudan a complementar y fortalecer la estructura del libro. Invitamos a nuestros lectores, desde su perspectiva de aprendizaje e interés académico, a emprender un nuevo viaje en la estructura y función inmunológica en la maravillosa profundidad de la piel.
Exocytosis and Endocytosis
In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.
Índice de Estado de Derecho en México 2020-2021
El Índice ofrece datos organizados en ocho factores que enmarcan el concepto de Estado de Derecho: 1) Límites al poder gubernamental, 2) Ausencia de corrupción, 3) Gobierno abierto, 4) Derechos fundamentales, 5) Orden y seguridad, 6) Cumplimiento regulatorio, 7) Justicia civil, y 8) Justicia penal. En conjunto, los resultados del Índice de Estado de Derecho en México 2020-2021 evidencian un estancamiento en el progreso del país hacia un Estado de Derecho robusto, con cambios marginales en los puntajes generales desde la última edición del Índice. Los puntajes de los ocho factores se desagregan en 42 sub-factores, los cuales reflejan las perspectivas y experiencias de más de 25,000 personas en todo el país, más de 2,300 especialistas en justicia civil, justicia penal, justicia laboral y salud pública (a quienes se entrevistó entre julio y octubre de 2020), así como resultados de una multiplicidad de encuestas y bases de datos de otras instituciones reconocidas en estos temas (fuentes terciarias).
Autophagy
Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen
Protein Blotting and Detection
Over the past thirty years, the development of the Western blot has revolutionized the fields of biomedical research and medical diagnostics. In "Protein Blotting and Detection: Methods and Protocols", expert researchers present numerous techniques based on the Western blot, providing detailed, readily reproducible methods, tips, and alternatives directly and easily transferable to the laboratory setting. Chapters offer a large number of variations on the theme of protein transfer to solid support followed by detection, presenting both adaptations of traditional techniques as well as completely original methods of protein blotting. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, a list of necessary materials, step-by-step methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Innovative and highly practical, Protein Blotting and Detection: Methods and Protocols is an essential, hands-on guide for all investigators who hope to bring these cutting-edge procedures home to their laboratories.
Who Creates New Firms When Local Opportunities Arise?
New firm formation is a critical driver of job creation, and an important contributor to the responsiveness of the economy to aggregate shocks. In this paper we examine the characteristics of the individuals who become entrepreneurs when local opportunities arise due to an increase in local demand. We identify local demand shocks by linking fluctuations in global commodity prices to municipality level agricultural endowments in Brazil. We find that the firm creation response is almost entirely driven by young and skilled individuals, as measured by their level of experience, education, and past occupations involving creativity, problem-solving and managerial roles. In contrast, we find no su...
Permanent Missions to the United Nations
This publication, often referred to as the "Blue Book," lists the names, addresses, emails, website URLs and phone numbers of all diplomatic representatives to the United Nations headquarters in New York City. This includes UN Member States maintaining permanent missions in the City; Non-member Observer States and entities; intergovernmental organizations; other entities; specialized agencies maintaining liaison offices at headquarters, as well as members of the principal organs of the United Nations and members of other standing organs of the UN. This publication is written in conjunction with the United Nations Protocol and Liaison Service at headquarters.
Mestiza Rhetorics
"This book collects and contextualizes thirty-three primary writings of understudies yet revolutionary Mexicana rhetors and social activists that were originally published in the late nineteenth and early twentieth centuries in Spanish-language presses in Mexico and the United States"--
The Prion Protein
A conformational transition of the cellular prion protein (PrPC) into an aberrantly folded isoform designated scrapie prion protein (PrPSc) is the hallmark of a variety of neurodegenerative disorders collectively called prion diseases. They include Creutzfeldt-Jakob disease and Gerstmann-Stäussler-Scheinker syndrome in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and chronic wasting disease (CWD) in free-ranging deer. In contrast to the deadly properties of misfolded PrP, PrPC seems to possess a neuroprotective activity. More-over, animal models indicated that the stress-protective activity of PrPC and the neurotoxic effects of PrPSc are somehow interconnected....
