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This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells functionally cooperate to guide behavioral responses? Two genetically tractable species, mice and flies, together significantly further our understanding of these processes. Current efforts focus on integrating knowledge gained from three interrelated fields of research: (1) understanding how the fates of different cell types are specified during development, (2) revealing the synaptic connections between identified cell types (“connectomics”) using high-resolution three-dimensional circuit anatomy, and (3) causal testing of how iden tified circuit elements contribute to visual perception and behavior.
The Senses: A Comprehensive Reference, Second Edition, Seven Volume Set is a comprehensive reference work covering the range of topics that constitute current knowledge of the neural mechanisms underlying the different senses. This important work provides the most up-to-date, cutting-edge, comprehensive reference combining volumes on all major sensory modalities in one set. Offering 264 chapters from a distinguished team of international experts, The Senses lays out current knowledge on the anatomy, physiology, and molecular biology of sensory organs, in a collection of comprehensive chapters spanning 4 volumes. Topics covered include the perception, psychophysics, and higher order processin...
Title of the first 10 volumes of the series is Germans to America : lists of passengers arriving at U.S. ports 1850-1855.
1. Themeanrestingmembranepotentialofrattaste cells is - 36 mVunderadap tation of the tongue to 41.4 mMNaCI and - 50mV under water adaptation. 2. The shapes ofreceptor potentials ofrattastecells inresponsetothe four basic tastestimuli(0.5MNaCI, 0.02 M Q-HCI, 0.01 MHCl, and0.5 M sucrose)are classified into three types, namely (1) a depolarization alone, (2) a depolariza tion preceded by a transient hyperpolarization, and (3) a hyperpolarization alone. No regenerative spike potentials are evoked in rat taste cells by chemical stimuli. The amplitude of rat taste cell responses increases with increasing concentrationofthe taste stimulus. Mostofthe rat taste cells show a multiple sensitivity in that single cells respond to various combinations of the four basic taste stimuli with depolarizations or hyperpolarizations. 3. The rise and fall times of depolarizing responses to 0.5 M NaCI are much shorter than those of depolarizing responses to the other three stimuli. The fall time of depolarization evoked by 0.01 M HCI is the longest. The rise and fall times of all hyperpolarizing responses are shorter than those of all de polarizing responses.