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Quantitative Aspects of Electrospray Mass Spectrometry
Electrospray is a new soft ionization technique that is able to produce large and fragile ions without fragmentation and with high sensitivity for mass spectrometric analysis. In this study various features of Mass Spectrometry with an Electrospray source have been investigated including effects extensive multiple charging of large molecules. A parametric study of electrospray mass spectrometry revealed the dependency of total as well as mass-selected ion currents on key experimental parameters. In particular the ion currents were shown to be approximately independent of liquid flow rate and to vary linearly with analyte concentration over a certain range. The ion yield as a function of anal...
Quantitative Proteomics by Mass Spectrometry
This volume is a compendium of cutting-edge protocols for quantitative proteomics, and presents the most significant methods used in the field today. The focus on mass spectrometry (MS) is integral. Attention is given to state-of-the-art techniques for the characterization of the phosphoproteome and tandem MS for detection of inborn errors of metabolism. This volume is an indispensable resource in the search for novel biomarkers.
Cell Biology
This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems. This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies. Topics covered include: Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocyt...
Ramsey Theory
This book explores the theory’s history, recent developments, and some promising future directions through invited surveys written by prominent researchers in the field. The first three surveys provide historical background on the subject; the last three address Euclidean Ramsey theory and related coloring problems. In addition, open problems posed throughout the volume and in the concluding open problem chapter will appeal to graduate students and mathematicians alike.
American Coverlets and Their Weavers
This lavishly illustrated guide to one of the premier collections of woven coverlets in the United States is an essential reference for collectors, historians, specialists in material culture, and all those who are interested in American textiles. Information about the lives and professional careers of more than seven hundred weavers is included. In-depth discussions explore fifty coverlets that are depicted in detail.
